110505-75-4

Basic information

• Product Name: PARA-TOPOLIN RIBOSIDE 99% (HPLC)
• Synonyms: PARA-TOPOLIN RIBOSIDE 99% (HPLC);N-[(4-Hydroxyphenyl)methyl]adenosine;N6-(4-Hydroxybenzyl)adenosine
• CAS NO: 110505-75-4
• Molecular Formula: C17H19N5O5
• Molecular Weight: 373.36326
• Mol File: 110505-75-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 201-204 °C(Solv: methanol (67-56-1); chloroform (67-66-3))
• Boiling Point: 753.2±70.0 °C(Predicted)
• Appearance: /
• Density: 1.71
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• PKA: 9.72±0.15(Predicted)
• CAS DataBase Reference: PARA-TOPOLIN RIBOSIDE 99% (HPLC)(CAS DataBase Reference)
• NIST Chemistry Reference: PARA-TOPOLIN RIBOSIDE 99% (HPLC)(110505-75-4)
• EPA Substance Registry System: PARA-TOPOLIN RIBOSIDE 99% (HPLC)(110505-75-4)

Safety Data

• Hazardous Substances Data: 110505-75-4(Hazardous Substances Data)

Usage

Description

PARA-TOPOLIN RIBOSIDE 99% (HPLC) is an endogenous compound extracted from G. elata, known for its potential sedative, hypnotic, neuroprotective, and therapeutic properties. It is a promising candidate for research and development in the pharmaceutical industry, particularly for the prevention and treatment of neurodegenerative diseases.

Uses

Used in Pharmaceutical Industry:
PARA-TOPOLIN RIBOSIDE 99% (HPLC) is used as a sedative and hypnotic agent for its potential calming and sleep-inducing effects. It is also utilized as a neuroprotective and therapeutic agent for the prevention and treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's, due to its ability to protect and repair neurons and promote overall brain health.

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 2004-06-0 6-Chloropurine riboside 
• 696-60-6 4-aminomethylphenol 
• 699-06-9 4-hydroxybenzaldehyde oxime 
• 1004-23-5 4-hydroxy-benzylamine hydrochloride 
• 80054-30-4 6-(4-hydroxybenzylamino)purine 
• 22164-16-5 7-methylguanosine 

Downstream Products

• 1375410-34-6 N6-(4-hydroxybenzyl)-2’,3’-O-isopropylidene-adenosine 

Relevant articles and documents

Synthesis of [15N4] purine labeled cytokinin glycosides derived from zeatins and topolins with 9-β-d, 7-β-d-glucopyranosyl, or 9-β-d-ribofuranosyl group

Synthesis of [15N4] purine labeled cytokinine glycosides derived from zeatins and topolins containing a 9-β-d, 7-β-d-glucopyranosyl, or 9-β-d-ribofuranosyl group is described. These N6-substituted adenine derivatives are i

APPLICATIONS OF N6-SUBSTITUTED ADENOSINE DERIVATIVE AND N6-SUBSTITUTED ADENINE DERIVATIVE TO CALMING, HYPNOSES, CONVULSION RESISTANCE, EPILEPTIC RESISTANCE, PARKINSON DISEASE RESISTANCE, AND DEMENTIA PREVENTION AND TREATMENT

PROBLEM TO BE SOLVED: To prepare analgesics, hypnotic agents, anticonvulsant agents, antiepileptics, antiparkinson drugs, dementia prophylactics, and health care food. SOLUTION: The present invention relates to an N6-substituted adenosine derivative and an N6-substituted adenine derivative selected from the group consisting of specific compounds. The present invention also relates to a pharmaceutical composition at least comprising a therapeutically effective amount of the compounds and a pharmaceutically acceptable carrier. The invention further relates to the compounds used in preparation of analgesics, hypnotic agents, anticonvulsant agents, antiepileptics, antiparkinson drugs, dementia prophylactics, and health care food. COPYRIGHT: (C)2016,JPO&INPIT

N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF

The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.