1105067-91-1 Usage
Description
Defluoro Atorvastatin Acetonide tert-Butyl Ester is an intermediate compound used in the synthesis of Atorvastatin impurities. It is a yellow solid with specific chemical properties that make it suitable for use in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Defluoro Atorvastatin Acetonide tert-Butyl Ester is used as an intermediate in the preparation of Atorvastatin impurities. It plays a crucial role in the synthesis process, ensuring the purity and quality of the final product, Atorvastatin, which is a widely used cholesterol-lowering drug.
Check Digit Verification of cas no
The CAS Registry Mumber 1105067-91-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,5,0,6 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1105067-91:
(9*1)+(8*1)+(7*0)+(6*5)+(5*0)+(4*6)+(3*7)+(2*9)+(1*1)=111
111 % 10 = 1
So 1105067-91-1 is a valid CAS Registry Number.
1105067-91-1Relevant articles and documents
Synthesis of some impurities and/or degradation products of atorvastatin
Stach, Jan,Havlicek, Jaroslav,Placek, Lukas,Radl, Stanislav
, p. 229 - 246 (2008/12/22)
Synthesis of some impurities and/or degradation products of atorvastatin, calcium (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl) pyrrol-1-yl]-3,5-dihydroxyheptanoate, is described. These include its desfluoro analog, the corresponding (3S,5S)-and (3S,5R)-epimers, atorvastatin lactone, and some other potential impurities. The synthesized compounds as well as the corresponding intermediates were characterized by 1H NMR, 13C NMR and MS.
