110658-85-0

Basic information

• Product Name: (-)-4(E),8(E),12(Z)-casbene
• CAS NO: 110658-85-0
• Molecular Weight: 272.474
• Mol File: 110658-85-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (-)-4(E),8(E),12(Z)-casbene(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-4(E),8(E),12(Z)-casbene(110658-85-0)
• EPA Substance Registry System: (-)-4(E),8(E),12(Z)-casbene(110658-85-0)

Safety Data

• Hazardous Substances Data: 110658-85-0(Hazardous Substances Data)

Upstream product

• 13920-11-1 2E,6E,10E-geranylgeranyl aldehyde 
• 110589-91-8 (+)-cis-2,2-dimethyl-3-<3,7-dimethyl-11-oxo-3(E),7(E)-dodecadienyl>cyclopropanecarbaldehyde 
• 1067-74-9 Methyl diethylphosphonoacetate 
• 5460-63-9 (+/-)-cis-Chrysanthemsaeure-methylester 
• 68254-38-6 (2E,6E,10E)-1-diazo-3,7,11,15-tetramethyl-hexadeca-2,6,10,14-tetraene 

Relevant articles and documents

Intramolecular cyclopropanation reactions of organozinc carbenoids derived from terpenoid enals

Treatment of a series of unsaturated terpenoid enals with 1,2 bis (chlorodimethylsilyl) ethane and zinc provides a simple and efficient method for intramolecular cyclopropanation.

Synthesis of Macrocyclic Terpenoid Hydrocarbons by Intramolecular Carbonyl Coupling: Bicyclogermacrene, Lepidozene, and Casbene

Total syntheses of two germacrane sesquiterpenes, bicyclogermacrene (1) and lepidozene (2), and of the cembrane sesquiterpene casbene (3) are discussed.Bicyclogermacrene and lepidozene were prepared in seven steps from geranylacetone by routes that involve titanium-induced cyclizations of cis- and trans-2,2-dimethyl-3-cyclopropanecarbaldehyde, respectively. (+)-Casbene was prepared from (+)-2-carene and 6-methyl-5-hepten-2-one by a route whose key steps were the palladium-catalysed cross-coupling of vinylic iodide 31 with homoallylic organozinc reagent 32 and titanium-induced cyclization of cis-2,2-dimethyl-3-cyclopropanecarbaldehyde (16).