110721-36-3

Basic information

• Product Name: Butanoic acid, 2-[[(1-methylcyclohexyl)oxy]imino]-3-oxo-, ethyl ester, (2Z)-
• CAS NO: 110721-36-3
• Molecular Formula: C13H21NO4
• Molecular Weight: 255.314
• Mol File: 110721-36-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-[[(1-methylcyclohexyl)oxy]imino]-3-oxo-, ethyl ester, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-[[(1-methylcyclohexyl)oxy]imino]-3-oxo-, ethyl ester, (2Z)-(110721-36-3)
• EPA Substance Registry System: Butanoic acid, 2-[[(1-methylcyclohexyl)oxy]imino]-3-oxo-, ethyl ester, (2Z)-(110721-36-3)

Safety Data

• Hazardous Substances Data: 110721-36-3(Hazardous Substances Data)

Upstream product

• 66508-93-8 ethyl 2-(hydroxyimino)-3-oxybutyrate 
• 931-77-1 1-bromo-1-methylcyclohexane 
• 2923-28-6 silver trifluoromethanesulfonate 
• 141-97-9 ethyl acetoacetate 
• 590-67-0 1-Methylcyclohexanol 

Downstream Products

• 110721-37-4 4-Bromo-2-[(Z)-1-methyl-cyclohexyloxyimino]-3-oxo-butyric acid ethyl ester 
• 110721-40-9 sodium 6β-<(Z)-2-(2-aminothiazol-4-yl)-2-(1-methylcyclohexyloxyimino)acetamido>penicillanate 
• 110721-39-6 S-2-pyridyl (Z)-2-(2-aminothiazol-4-yl)-2-(1-methylcyclohexyloxyimino)thioacetate 
• 110721-38-5 ethyl (Z)-2-(2-aminothiazol-4-yl)-2-(1-methylcyclohexyloxyimino)acetate 
• 110749-05-8 (Z)-2-(2-aminothiazol-4-yl)-2-(1-methylcyclohexyloxyimino)acetic acid 

Relevant articles and documents

&β-Lactamase-Stable Penicillins. Synthesis and Structure-Activity Relationships of (Z)-Alkyloxyimino Penicillins; Selection of BRL 44154

A series of (Z)-2-alkyloxyimino-2-(2-aminothiazol-4-yl)acetamidopenicillins has been prepared.New methodology has been developed to prepare tertiary alkyl oximes.High stability to β-lactamases and potent antibacterial activity have been achieved against Gram-positive and certain Gram-negative organisms.Activity against methicillin-resistant Staphylococcus aureus was an unexpected finding.The cyclopentyl analogue 4f, BRL 44154, has been selected for further study.