110829-23-7

Basic information

• Product Name: Z-3-thiosemicarbazone of 1-acetylisatin
• Synonyms: Z-3-thiosemicarbazone of 1-acetylisatin
• CAS NO: 110829-23-7
• Molecular Weight: 262.292
• Mol File: 110829-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Z-3-thiosemicarbazone of 1-acetylisatin(CAS DataBase Reference)
• NIST Chemistry Reference: Z-3-thiosemicarbazone of 1-acetylisatin(110829-23-7)
• EPA Substance Registry System: Z-3-thiosemicarbazone of 1-acetylisatin(110829-23-7)

Safety Data

• Hazardous Substances Data: 110829-23-7(Hazardous Substances Data)

Upstream product

• 574-17-4 1-acetyl-1H-indole-2,3-dione 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 487-16-1 (Z)-2-(2-oxoindolin-3-ylidene)-hydrazinecarbothioamide 

Relevant articles and documents

SEMICARBAZONES AND THIOSEMICARBAZONES OF THE HETEROCYCLIC SERIES. XLVIII. REACTION OF 1-ACETYLISATINS WITH THIOSEMICARBAZIDES

In reaction with thiosemicarbazides 1-acylisatins form the thiosemicarbazides of N-acylisatinic acids in addition to the thiosemicarbazones.The yields of the thiosemicarbazides increase with increase in the electron-withdrawing effect of the acyl residue or with substitution of a hydrogen atom in the primary thioamide group of the initial thiosemicarbazides by alkyl radicals.The reaction products are capable of transformation to the 3-thiosemicarbazones of 1-acylisatins.The latter were isolated in the form of E and Z isomers, and their mutual transitions were investigated.The five-membered ring of 1-acetylisatin thiosemi carbazone opens in an alkaline medium with the formation of the thiosemicarbazone of N-acetylisatinic acid.Contrary to previous data, this compound does not undergo direct cyclization to the 1,2,4-triazinoindole derivatives.