110958-23-1 Usage
Description
(S)-5-(piperidine-1-carbonyl)pyrrolidin-2-one, also known as (S)-Proline 3-carbamate, is a chemical compound with the molecular formula C11H18N2O2. It is a proline derivative, which is a cyclic amino acid commonly found in nature and essential for the synthesis of proteins and peptides. (S)-5-(piperidine-1-carbonyl)pyrrolidin-2-one is a white solid with a molecular weight of 206.27 g/mol and a melting point of around 90-95°C. It is recognized for its potential biological activities and medicinal properties, making it a valuable compound in pharmaceutical research and organic synthesis.
Uses
Used in Pharmaceutical Research:
(S)-5-(piperidine-1-carbonyl)pyrrolidin-2-one is used as a key compound in the development and synthesis of new drugs for various medical applications. Its unique structure and properties contribute to the creation of innovative pharmaceuticals that can address a range of health issues.
Used in Organic Synthesis:
In the field of organic chemistry, (S)-5-(piperidine-1-carbonyl)pyrrolidin-2-one serves as a building block for the production of various compounds. Its versatility allows it to be incorporated into different chemical reactions, leading to the synthesis of a wide array of molecules with diverse applications.
Used in Chemical Production:
(S)-5-(piperidine-1-carbonyl)pyrrolidin-2-one is also utilized as an essential component in the manufacturing process of certain chemical products. Its presence in these processes can enhance the properties of the final products, making them more effective or efficient for their intended uses.
Check Digit Verification of cas no
The CAS Registry Mumber 110958-23-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,9,5 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 110958-23:
(8*1)+(7*1)+(6*0)+(5*9)+(4*5)+(3*8)+(2*2)+(1*3)=111
111 % 10 = 1
So 110958-23-1 is a valid CAS Registry Number.
110958-23-1Relevant articles and documents
DIBAL-H-H2NR and DIBAL-H-HNR1R2·HCl complexes for efficient conversion of lactones and esters to amides
Huang, Pei-Qiang,Zheng, Xiao,Deng, Xian-Ming
, p. 9039 - 9041 (2001)
The reaction of a lactone or an ester with organoaluminum species generated from DIBAL-H-H2NR or DIBAL-H-HNR1R2·HCl complexes provided efficient methods for preparation of amides. Conditions were defined for the preparation of both secondary and tertiary amides, including Weinreb amides in excellent yields.
Synthesis of chiral diamines using novel 2-trichloromethyloxazolidin-4-one precursors derived from 5-oxo-proline and proline
Amedjkouh, Mohamed,Ahlberg, Per
, p. 2229 - 2234 (2007/10/03)
Efficient syntheses of chiral vicinal diamines derived from (S)-oxo-proline and (S)-proline are described. The novel diastereomerically pure precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo-[3.3.0]-octan-4,8-dione 3 and its enantiomer are readily available by reaction of the inexpensive enantiomers of 5-oxo-proline with chloral. Compound 3 reacts with primary and secondary amines to afford the 5-oxo-prolylamides 4 in quantitative yield. In contrast, the (S)-proline-derived precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one 6 gave (S)-N-formylprolylamides 9 and/or (S)-prolylamides 8 depending on the reaction conditions. Upon reduction with LiAlH4, amides 4 and 9 afforded the proline-derived (S)-2-(alkylaminomethyl)pyrrolidines 1 and (S)-N-methyl-2-(alkylaminomethyl)-pyrrolidines 5 in 70-90% yields.