11100-45-1

Basic information

• Product Name: ENTEROTOXIN TYPE B, STAPHYLOCOCCUS AUREUS
• Synonyms: ENTEROTOXIN TYPE B;ENTEROTOXIN TYPE B, STAPHYLOCOCCUS AUREUS;STAPHYLOCOCCAL ENTEROTOXIN B;SEB;entero-toxin(staphylococcusreduced);enterotoxinb,staphylococcal;STAPHYLOCOCCAL ENTEROTOXIN B FROM*STAPHY LOCOCCUS AU;staphylococcal enterotoxin b from staphylococcus aureus
• CAS NO: 11100-45-1
• Molecular Weight: 0
• Mol File: 11100-45-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ENTEROTOXIN TYPE B, STAPHYLOCOCCUS AUREUS(CAS DataBase Reference)
• NIST Chemistry Reference: ENTEROTOXIN TYPE B, STAPHYLOCOCCUS AUREUS(11100-45-1)
• EPA Substance Registry System: ENTEROTOXIN TYPE B, STAPHYLOCOCCUS AUREUS(11100-45-1)

Safety Data

• Hazard Codes: Xn,T+
• Statements: 20/22-36-26/27/28
• Safety Statements: 22-24/25-36/37-45-28-26
• RIDADR: UN 3462 6.1/PG 3
• WGK Germany: 3
• RTECS: XW5807700
• Hazardous Substances Data: 11100-45-1(Hazardous Substances Data)

Usage

Description

Enterotoxin Type B, Staphylococcus aureus, also known as Staphylococcal enterotoxin B (SEB), is a potent superantigen produced by the bacterium Staphylococcus aureus. It has the ability to bind to MHC class II molecules and specific Vβ regions of T cell receptors (TCR), leading to the activation of both monocytes/macrophages and T lymphocytes. This unique property makes SEB a valuable tool in the study and manipulation of the immune system.

Uses

Used in Immunology Research:
SEB is used as a superantigen and immune system activator in various immunological research applications. Its ability to activate a large proportion of T cells makes it a useful tool for studying T cell activation, immune responses, and the mechanisms of superantigens.
Used in SEB Detection Systems Development:
SEB may be used as a reference material in the development of SEB detection systems. These systems are crucial for the detection and monitoring of SEB in various settings, such as food safety, biodefense, and clinical diagnostics. The development of sensitive and specific detection methods is essential for ensuring public health and safety.
Used in Drug Development:
SEB's immunomodulatory properties make it a potential candidate for drug development. Researchers are exploring its potential use in the treatment of various immune-related disorders, such as autoimmune diseases and inflammatory conditions, by modulating the immune response.
Used in Vaccine Development:
SEB's ability to activate the immune system also makes it a valuable component in vaccine development. It can be used as an adjuvant to enhance the immune response to vaccines, potentially improving their efficacy and effectiveness in preventing infectious diseases.
Used in Biodefense:
SEB's potential use as a biological threat agent necessitates the development of countermeasures and medical countermeasures. Research on SEB's properties and effects on the immune system can contribute to the development of therapeutics and vaccines to protect against its harmful effects in the event of a bioterrorism attack.

Hazard

A poison.

Biochem/physiol Actions

A superantigen for T-lymphocytes. Activator of the immune system that binds to major histocompatibility complex (MHC) antigens and CD28.