111017-66-4

Basic information

• Product Name: (Z)-2(2,3-dimethoxybenzylidene)benzofuran-3(2H)-one
• Synonyms: (Z)-2(2,3-dimethoxybenzylidene)benzofuran-3(2H)-one
• CAS NO: 111017-66-4
• Molecular Weight: 282.296
• Mol File: 111017-66-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-2(2,3-dimethoxybenzylidene)benzofuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2(2,3-dimethoxybenzylidene)benzofuran-3(2H)-one(111017-66-4)
• EPA Substance Registry System: (Z)-2(2,3-dimethoxybenzylidene)benzofuran-3(2H)-one(111017-66-4)

Safety Data

• Hazardous Substances Data: 111017-66-4(Hazardous Substances Data)

Upstream product

• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 118-93-4 o-hydroxyacetophenone 
• 42220-80-4 2'',3''-dimethoxy-2'-hydroxychalcone 
• 34000-33-4 (E)-3-(2,3-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one 
• 7169-34-8 3-oxo-2,3-dihydrobenzo[b]furan 

Relevant articles and documents

Aurones as histone deacetylase inhibitors: Identification of key features

In this study, a total of 22 flavonoids were tested for their HDAC inhibitory activity using fluorimetric and BRET-based assays. Four aurones were found to be active in both assays and showed IC50 values below 20 μM in the enzymatic assay. Molecular modelling revealed that the presence of hydroxyl groups was responsible for good compound orientation within the isoenzyme catalytic site and zinc chelation.