111041-97-5 Usage
Description
1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole is a chemical compound with the molecular formula C6H5N5O3. It is a derivative of 1,2,4-triazole and is classified as a nitrofuran, which is a class of organic compounds containing a furan ring with a nitro group attached. 1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole is known for its antimicrobial and antitumor properties, and it has been studied for its potential use as a pharmaceutical agent.
Uses
Used in Pharmaceutical Industry:
1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole is used as an antimicrobial agent for its ability to inhibit the growth of various microorganisms, making it a potential candidate for treating infections caused by bacteria and other pathogens.
1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole is also used as an antitumor agent for its potential to combat cancer cells. Its antitumor properties make it a promising candidate for the development of new cancer treatments, as it may help in inhibiting the growth and proliferation of tumor cells.
Additionally, due to its chemical structure and properties, 1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole could potentially be used in other applications within the pharmaceutical industry, such as in the development of new drugs or drug delivery systems. However, further research and development would be required to explore these possibilities.
Check Digit Verification of cas no
The CAS Registry Mumber 111041-97-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,0,4 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 111041-97:
(8*1)+(7*1)+(6*1)+(5*0)+(4*4)+(3*1)+(2*9)+(1*7)=65
65 % 10 = 5
So 111041-97-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5N5O3/c13-12(14)7-2-1-6(15-7)3-9-11-5-8-4-10-11/h1-5H/b9-3+
111041-97-5Relevant articles and documents
Formal potentials of new analogues of nifurtimox: Relationship to activity
Cerecetto,Mester,Onetto,Seoane,Gonzalez,Zinola
, p. 1207 - 1213 (2007/10/02)
Electrochemical studies (Formal Potentials and Coulometry) were performed on several analogues of Nifurtimox, in order to gain insight on the proposed mechanism of action of these drugs. It is thought that Nifurtimox shows part of its trypanocidal activity via an electron transfer process, leading to the production of active oxygen species that kill the parasite. Formal potentials provide relevant data about the feasibility of electron transfer in vivo. All analogues tested contained the nitro group, which is the most easily reducible group in the parent drug Nifurtimox. The formal potentials values determined ranged from -1,86 to -0,46 V. Coulometric runs were carried out to study the one-electron transfer process. A good correlation between formal potentials and biological activity was found.
