111138-48-8

Basic information

• Product Name: 1,2-Cyclopentanedicarboxylic acid, monomethyl ester, (1S,2S)-
• Synonyms: (1S,2S)-Cyclopentane-1,2-dicarboxylic acid monomethyl ester;(1S,2S)-2-(methoxycarbonyl)cyclopentanecarboxylic acid;Rac-trans-cyclopentane-1,2-dicarboxylic acid monomethyl ester;trans-cyclopentane-1,2-dicarboxylic acid monomethyl ester
• CAS NO: 111138-48-8
• Molecular Formula: C8H12O4
• Molecular Weight: 172.181
• Mol File: 111138-48-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Cyclopentanedicarboxylic acid, monomethyl ester, (1S,2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Cyclopentanedicarboxylic acid, monomethyl ester, (1S,2S)-(111138-48-8)
• EPA Substance Registry System: 1,2-Cyclopentanedicarboxylic acid, monomethyl ester, (1S,2S)-(111138-48-8)

Safety Data

• Hazardous Substances Data: 111138-48-8(Hazardous Substances Data)

Usage

Explanation

The compound is derived from cyclopentanedicarboxylic acid and is a monomethyl ester.

Explanation

The presence of a single methyl group in the ester indicates that it is a monomethyl ester.

Explanation

This notation represents the spatial arrangement of the atoms in the molecule, which is crucial for its chemical properties and reactivity.

Explanation

The compound is derived from cyclopentanedicarboxylic acid, which is the parent compound.

Explanation

The compound may be used in various applications, depending on its specific properties and potential uses in the field of chemistry.

Explanation

The molecular structure consists of a five-membered ring with two carboxylic acid groups and a methyl ester group attached.

Explanation

The compound contains carboxylic acid, ester, and cyclic functional groups, which contribute to its chemical properties.

Explanation

The presence of chiral centers at carbons 1 and 2 indicates that the compound has stereoisomers, which can have different properties and reactivities.

Explanation

The compound is likely to be soluble in organic solvents, such as ethanol, methanol, or acetone, due to its ester and cyclic structures.

Explanation

The compound is expected to be stable under normal conditions, such as room temperature and pressure, without undergoing significant decomposition or reaction.

Monomethyl Ester

Contains a single methyl group attached to the carboxylic acid group.

Stereochemistry

(1S,2S)designation.

Parent Compound

Cyclopentanedicarboxylic acid.

Applications

Building block in the synthesis of other compounds or as a component in formulations for specific industrial or research purposes.

Molecular Structure

Cyclic structure with two carboxylic acid groups and a methyl ester group.

Functional Groups

Carboxylic acid, ester, and cyclic.

Chirality

Chiral center at carbons 1 and 2.

Solubility

Soluble in organic solvents.

Stability

Stable under normal conditions.

Upstream product

• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 1461-96-7 cis-1,2-cyclopentanedicarboxylic acid 
• 35878-28-5 cyclopentane-cis-1,2-dicarboxylic acid anhydride 
• 67-56-1 methanol 
• 80656-14-0 trans-1,2-cyclopentanedicarboxylic acid 

Downstream Products

• 277751-15-2 trans-methyl (1S,2S)-2-{4-[amino(benzyloxycarbonylimino)methyl]benzylaminocarbonyl}cyclopentanecarboxylate 
• 1445591-80-9 (1S,2S)-1-(2-(4-bromophenyl)-2-oxoethyl) 2-methyl cyclopentane-1,2-dicarboxylate 
• 1445590-56-6 (1,2-trans)-N-benzyl-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)cyclopentanecarboxamide 
• 1445589-06-9 (S)-tert-butyl 2-(5-(4-(2-((1S,2S)-2-((R)-3-methylmorpholine-4-carbonyl)cyclopentyl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate 
• 1445590-70-4 ((1S,2S)-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)cyclopentyl)((R)-3-methylmorpholino)methanone 
• 1445591-81-0 (1S,2S)-methyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)cyclopentanecarboxylate 
• 1445589-63-8 methyl ((S)-3-hydroxy-1-((S)-2-(5-(4-(2-((1S,2S)-2-((R)-3-methylmorpholine-4-carbonyl)cyclopentyl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-1-oxopropan-2-yl)carbamate 
• 889888-75-9 (1S,2S)-cyclopentane-1,2-dicarboxylic acid 1-[(2'-hydroxy-1'-(S)-tert-butylethyl)-amide]-2-[(2''-hydroxy-1''-(R)-phenylethyl)-amide] 
• 889888-73-7 (1S,2S)-cyclopentane-1,2-dicarboxylic acid 1-[(2'-hydroxy-1'-(S)-tert-butylethyl)-amide]-2-[(2''-hydroxy-1''-(S)-phenylethyl)-amide] 

Relevant articles and documents

NOVEL HEPATITIS C VIRUS INHIBITORS

The invention provides compounds of formula (I): wherein Rings A and A' are independently 5-membered optionally substituted aromatic heterocycles; Q is C(=O)NR1R1' or formula U is C(R4)2, O, S, S(=O)2, C(R4)2C(R4)2, CH2O, OCH2, CH2S, SCH2, CH2S(=O)2, S(=O)CH2 or C=C(Ru )2; X is CH2, CHR12, CR12R12, O, S, S(=O)2 or NRx; m is 0, 1, 2 or 3; n is 0, 1, 2 or 3; the other variables are as defined in the claims, which are of use in the treatment or prophylaxis of hepatitis C virus infection, and related aspects.