1112262-71-1

Basic information

• Product Name: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester
• Synonyms: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester
• CAS NO: 1112262-71-1
• Molecular Weight: 640.795
• Mol File: 1112262-71-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester(1112262-71-1)
• EPA Substance Registry System: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester(1112262-71-1)

Safety Data

• Hazardous Substances Data: 1112262-71-1(Hazardous Substances Data)

Usage

Uses

Isopropyl Acetonide Atorvastatin is an intermediate of Atorvastatin(A134525).

Upstream product

• 1426655-65-3 (R)-isopropyl 7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-pheny1-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-3-oxoheptanoate 
• 1035205-25-4 (3R,5R)-isopropyl 7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate 
• 77-76-9 2,2-dimethoxy-propane 
• 110862-46-9 5-(4-fluorophenyl)-2-(1-methylethyl)-1-(3-oxopropyl)-N,4-diphenyl-1H-pyrrole-3-carboxamide 
• 1363159-12-9 C₁₃H₂₁NO₄ 
• 1363159-13-0 C₂H₂O₄*C₁₃H₂₅NO₄ 
• 1112262-76-6 C₁₃H₂₅NO₄ 
• 1363159-14-1 C₅H₁₀O₂*C₁₃H₂₅NO₄ 
• 125971-96-2 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide 
• 1112262-69-7 phthalimido acetonide isopropyl ester 
• 1112262-65-3 7-(1,3-dioxo-1,3-dihydro-isoindo-2-yl)-3,5-dihydroxy-heptanoic acid 
• 1112262-62-0 2-[2-(4-hydroxy-6-oxo)-tetrahydro-pyran-2-yl]-isoindole-1,3-dione 

Downstream Products

• 134523-03-8 lipitor 

Relevant articles and documents

Synthetic studies on statins. Part 1: A short and cyanide-free synthesis of atorvastatin calcium via an enantioselective aldol strategy

A short and cyanide-free enantioselective synthesis of atorvastatin calcium has been achieved starting from a commercially available highly substituted 1,4-diketone in an overall yield of 40%. The key step in this approach is the asymmetric aldol reaction of an aldehyde with diketene in the presence of Ti(O-i-Pr)4-Schiff base complex to create the (5R)-stereochemistry of atorvastatin calcium.

Process for Preparing Chiral Compounds

The present invention is directed to a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process for making chiral compounds.