1113-83-3 Usage
Description
N-Glycolylneuraminic acid, also known as Neu5Gc, is a naturally occurring modified sugar and a derivative of neuraminic acid. It is an N-acylneuraminic acid with a glycolyl group as the acyl substituent on nitrogen and has a beta-configuration at the anomeric center. This white crystalline solid is a component of various biological systems and has been the subject of research for its role in different applications.
Uses
Used in Medical Research:
N-Glycolylneuraminic acid is used as a reference compound for analyzing changes in the glycome during lactation. It helps researchers understand the variations in the glycome composition, which can be crucial for studying the development and health of infants.
Used in Xenotransplantation:
N-Glycolylneuraminic acid, being a xenoantigen, is involved in antigenic reactions, particularly antibody-mediated hyperacute rejection, during xenotransplantation. This application is significant for the field of organ transplantation, as it aids in understanding the immune response and compatibility issues between species.
Used in Regulation of Biosynthesis:
The regulation of N-glycolylneuraminic acid biosynthesis in rat and mouse liver is another area of interest. Studying this process can provide insights into the metabolic pathways and potential therapeutic targets for various diseases and conditions related to glycosylation.
Check Digit Verification of cas no
The CAS Registry Mumber 1113-83-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,1 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1113-83:
(6*1)+(5*1)+(4*1)+(3*3)+(2*8)+(1*3)=43
43 % 10 = 3
So 1113-83-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H17NO10/c12-1-3(14)6(16)7(17)5(11-4(15)2-13)8(18)9(19)10(20)21/h3,5-8,12-14,16-18H,1-2H2,(H,11,15)(H,20,21)/t3-,5+,6-,7-,8-/m1/s1
