111460-87-8

Basic information

• Product Name: (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-propanone 2,2-dimethyl-trimethylene acetal
• Synonyms: (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-propanone 2,2-dimethyl-trimethylene acetal
• CAS NO: 111460-87-8
• Molecular Weight: 294.391
• Mol File: 111460-87-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-propanone 2,2-dimethyl-trimethylene acetal(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-propanone 2,2-dimethyl-trimethylene acetal(111460-87-8)
• EPA Substance Registry System: (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-propanone 2,2-dimethyl-trimethylene acetal(111460-87-8)

Safety Data

• Hazardous Substances Data: 111460-87-8(Hazardous Substances Data)

Upstream product

• 111199-07-6 (S)-2-hydroxy-3,N,N-trimethylbutanamide 
• 24347-63-5 methyl (S)-2-hydroxy-3-methylbutanoate 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 72-18-4 L-valine 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 111197-80-9 (S)-2-hydroxy-1-(4-methoxyphenyl)-3-methyl-1-butanone 

Downstream Products

• 111197-99-0 3-hydroxy-2,2-dimethylpropyl (S)-2-(4-methoxyphenyl)-3-methylbutanoate 
• 111197-91-2 (S)-2-methylsulfonyloxy-1-(4-methoxyphenyl)-3-methyl-1-butanone 2,2-dimethyl-trimethylene acetal 

Relevant articles and documents

A General Synthetic Method of Chiral 2-Arylalkanoic Esters via Thermal 1,2-Rearrangement

(S)-1-Aryl-2-sulfonyloxy-1-alkanone acetals, prepared from natural ethyl (S)-lactate or (S)-valine (chiral sources) by the use of a Grignard reaction, were rearranged under hydrolytic conditions in the presence of a base to give (S)-2-arylalkanoic esters which in general, showed much higher pharmacological activities than their antipodes.