111469-10-4

Basic information

• Product Name: 2-hexyl-1,4-bis<(benzyloxycarbonyl)amino>butane
• CAS NO: 111469-10-4
• Molecular Weight: 440.583
• Mol File: 111469-10-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hexyl-1,4-bis<(benzyloxycarbonyl)amino>butane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hexyl-1,4-bis<(benzyloxycarbonyl)amino>butane(111469-10-4)
• EPA Substance Registry System: 2-hexyl-1,4-bis<(benzyloxycarbonyl)amino>butane(111469-10-4)

Safety Data

• Hazardous Substances Data: 111469-10-4(Hazardous Substances Data)

Upstream product

• 111469-02-4 2,4,5-triiodo-3-hexanoylpyrrole 
• 111469-05-7 1-(1H-pyrrol-3-yl)hexan-1-one 
• 1551-07-1 3-n-hexylpyrrole 
• 501-53-1 benzyl chloroformate 

Relevant articles and documents

Synthesis of 2-Alkylputrescines from 3-Alkylpyrroles

Acylation of 2-(trichloroacetyl)pyrrole gave the 4-acyl derivatives (from 4-formyl to 4-hexanoyl) in good yields.Alkaline treatment gave corresponding 4-acyl-2-pyrrolecarboxylic acids, were decarboxylated to the 3-acylpyrroles by prior conversion to the 3-acyl-2,4,5-triiodopyrroles followed by hydrogenolysis.The 3-acylpyrroles were reduced by treatment with hydrazine in alkaline medium to the 3-alkylpyrroles.The latter were ring-opened by treatment with hydroxylamine in the presence of bicarbonate to give the dioximes of the corresponding 2-alkylsuccinaldehydes, which were then reduced to the 2-alkylpurescines (1,4-diaminobutanes).Ring-opening of 2,3-dimethylpyrrole followed by reduction of the dioxime gave 1,2-dimethylputrescine; the same sequence gave 1,3-dimethylputrescine from 2,4-dimethylpyrrole, while 3,4-dimethylpyrrole did not ring-open and gave the dioxime of 3,4-dimethylmaleimide.