1116-13-8

Basic information

• Product Name: N-LAUROYL-L-ASPARTIC ACID*
• Synonyms: N-LAUROYL-L-ASPARTIC ACID*
• CAS NO: 1116-13-8
• Molecular Formula: C16H29NO5
• Molecular Weight: 315.40516
• Mol File: 1116-13-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-LAUROYL-L-ASPARTIC ACID*(CAS DataBase Reference)
• NIST Chemistry Reference: N-LAUROYL-L-ASPARTIC ACID*(1116-13-8)
• EPA Substance Registry System: N-LAUROYL-L-ASPARTIC ACID*(1116-13-8)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 1116-13-8(Hazardous Substances Data)

Usage

General Description

N-LAUROYL-L-ASPARTIC ACID is a synthetic compound commonly used in personal care products and cosmetics as a surfactant and skin conditioning agent. It is an amino acid derivative with a lauric acid side chain, derived from coconut oil, and an aspartic acid moiety. As a surfactant, N-LAUROYL-L-ASPARTIC ACID has excellent cleansing and foaming properties, making it an ideal ingredient for shampoos, body washes, and facial cleansers. Its skin conditioning properties help to moisturize and soften the skin, making it a valuable addition to moisturizers, lotions, and creams. N-LAUROYL-L-ASPARTIC ACID is considered safe for use in cosmetics and personal care products when used according to established guidelines.

Upstream product

• 112-16-3 n-dodecanoyl chloride 
• 143-07-7 lauric acid 
• 56-84-8 L-Aspartic acid 
• 3792-50-5 L-aspartic acid monosodium salt 
• 1182-15-6 N^α-lauryl-L-aspartic acid dibenzyl ester 
• 3792-50-5 L-aspartic acid disodium salt 

Relevant articles and documents

Preparation method and application of amido carboxylic acid compound

The invention discloses a preparation method and application of an amido carboxylic acid compound. The preparation method comprises the step of subjecting organic carboxylic acid with a structure represented by a formula (I) shown in the description and an amino acid compound with a structure represented by a formula (II) shown in the description to a grinding reaction in the presence of a coupling reagent, thereby preparing the amido carboxylic acid compound with a structure represented by a formula (III) shown in the description. The product prepared by the method is high in yield, is energy-saving and environmentally friendly and does not need aftertreatment. According to the application, the amido carboxylic acid compound is applied to mineral flotation separation as a collector, and the collector has relatively high collection capability and relatively good selectivity and is particularly applicable to the flotation separation of minerals such as wolframite, scheelite, rare earthminerals, cassiterite, ilmenite, bauxite, manganese oxide ores, phosphorite and fluorite.

Isolation and total synthesis of gymnastatin N, a POLO-like kinase 1 active constituent from the fungus Arachniotus punctatus

A high throughput screen against POLO-like kinase 1 (Plk1), an anti-cancer target, identified an active extract from the fungus Arachniotus punctatus. Bioassay guided fractionation led to the isolation of the new natural product, gymnastatin N (1) and the known compound aranorosinol A (2) with IC50 values of 13 and 118 μM, respectively. A 12′-hydroxy analog of gymnastatin N, 3, was also isolated as a minor component. Gymnastatin N (1) was found to be a 52:48 mixture of (1S,6′R) and (1R,6′R) diastereomers, by synthesis of the four possible diastereomers and comparison of the optical rotation and chiral HPLC profile of each diastereoisomer with the natural product. Analogues of 1 were synthesized and evaluated against the Plk1 assay and these SAR studies suggested that the diene and free carboxylic acid moieties might be responsible for its bioactivity. Graphical Abstract.

Cosmetic composition containing DOPA derivatives

A composition for topical application to human hair or skin contains a chemical analogue of dihydroxyphenyl alanine (DOPA). This chemical analogue can be absorbed by skin or by a hair follicle and metabolised in-vivo, thus leading to the formation of melanin in skin or to the growth of melanin-pigmented hair. Consequently the composition can give controlled skin darkening to mimic sun-induced tanning or can bring about the growth of dar hair in place of the grey or white hair.