1116-40-1 Usage
Description
Triisobutylamine is a clear pale yellow liquid that possesses flammable chemical properties. It is a compound with a wide range of applications across different industries due to its unique characteristics.
Uses
Used in Mass Spectrometry (MALDI-MS):
Triisobutylamine is used as a component in developing second-generation ionic liquid matrices for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) of peptides, proteins, and carbohydrates. It enhances the efficiency and accuracy of mass spectrometry analysis in this application.
Used in Chemical Separation Processes:
In the chemical industry, Triisobutylamine is utilized for the separation of cis-fatty acid salts and trans-fatty acid (elaidic acid) salts. It is employed in conjunction with a new organic solvent nanofiltration membrane based on polydicyclopentadiene, which aids in the efficient separation of these compounds.
Used in the Synthesis of Acroyl Ammonium Derivatives:
Triisobutylamine serves as a base in the synthesis of acroyl ammonium derivatives, which are important compounds in various chemical and pharmaceutical applications. Its use in this process contributes to the production of valuable chemical intermediates and final products.
Production Methods
Triisobutylamine is manufactured from isobutanol and
ammonia under heat and pressure.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
TRIISOBUTYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: Toxic.
Fire Hazard
TRIISOBUTYLAMINE is combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 1116-40-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,1 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1116-40:
(6*1)+(5*1)+(4*1)+(3*6)+(2*4)+(1*0)=41
41 % 10 = 1
So 1116-40-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H27N/c1-10(2)7-13(8-11(3)4)9-12(5)6/h10-12H,7-9H2,1-6H3
1116-40-1Relevant articles and documents
One-Pot Synthesis of Symmetrical Tertiary and Secondary Amines from Carbonyl Compounds, Ammonium Carbonate and Carbon Monoxide as a Reductant
Muratov, Karim,Afanasyev, Oleg I.,Kuchuk, Ekaterina,Runikhina, Sofiya,Chusov, Denis
supporting information, p. 6557 - 6560 (2019/10/22)
Rh-catalyzed one-step synthesis of tertiary and secondary amines from aldehydes and ketones, ammonium carbonate serving as nitrogen source, and carbon monoxide as a reducing agent has been developed. Aliphatic and aromatic aldehydes lead to the corresponding tertiary symmetrical amines in 69–83 % yields. Aromatic and aliphatic ketones lead to the corresponding secondary symmetrical amines which were obtained in 62–79 % yields.
An efficient synthesis of tertiary amines from nitriles in aprotic solvents
Shares, Jonathan,Yehl, Jenna,Kowalsick, Amanda,Byers, Philip,Haaf, Michael P.
experimental part, p. 4426 - 4428 (2012/09/25)
Tertiary amines are utilized extensively as non-nucleophilic proton scavengers for a number of organic transformations. Herein we report the efficient syntheses of tertiary alkyl amines from their corresponding alkyl nitriles in the presence of a heterogeneous palladium catalyst and a source of dihydrogen in aprotic solvents. The reaction is atom economic, the conditions are mild, and the isolated yields are virtually quantitative. The degree of amine alkylation shows some solvent dependency; in polar protic solvents such as ethanol or methanol, the reaction affords a mixture of products with the secondary alkyl amine as the major product.
REDUCTIVE AMINATION OF ISOBUTYRALDEHYDE TO ISOBUTYLAMINES IN PRESENCE OF VARIOUS HYDROGENATION CATALYSTS
Smaeva, T. P.,Yakushin, M. I.,Akulova, N. G.,Bazyleva, R. V.,Lebedeva, N. V.
, p. 1039 - 1043 (2007/10/02)
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