1116680-15-9Relevant articles and documents
The discovery of azepane sulfonamides as potent 11β-HSD1 inhibitors
Neelamkavil, Santhosh F.,Boyle, Craig D.,Chackalamannil, Samuel,Greenlee, William J.,Zhang, Lili,Terracina, Giuseppe
scheme or table, p. 4563 - 4565 (2010/04/05)
Discovery of a series of azepine sulfonamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is described. SAR studies at the 4-position of the azepane ring have resulted in the discovery of a very potent compound 30 which has