1117893-60-3

Basic information

• Product Name: 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
• Synonyms: 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
• CAS NO: 1117893-60-3
• Molecular Formula: C14H16N2O5
• Molecular Weight: 292.291
• Mol File: 1117893-60-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one(1117893-60-3)
• EPA Substance Registry System: 3-(4-(4-Morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one(1117893-60-3)

Safety Data

• Hazardous Substances Data: 1117893-60-3(Hazardous Substances Data)

Usage

Structure

Heterocyclic organic compound

Rings

Morpholine ring, oxazolidinone ring

Functional groups

Phenyl, hydroxymethyl

Potential uses

Chemical reactions, pharmaceutical applications

Therapeutic activities

Potentially therapeutic

Implications

Development of new drugs

Interest

Further research potential, application in various fields

Upstream product

• 1313613-18-1 [4-(3-oxo-morpholin-4-yl)phenyl]carbamic acid benzyl ester 
• 60456-26-0 (R)-glycidyl butyrate 
• 122-98-5 2-Anilinoethanol 
• 438056-69-0 4-(4-aminophenyl)morpholin-3-one 
• 446292-04-2 4-(4-nitrophenyl)-3-morpholinone 
• 29518-11-4 4-phenylmorpholin-3-one 
• 124-38-9 carbon dioxide 
• 1447919-71-2 4-(4-((R)-5-((phenyloxycarbonyloxy)methyl)-2-oxo-oxazolidin-3-yl)phenyl)-morpholin-3-one 
• 1447919-69-8 acetic acid-1-benzyloxymethyl-2-{[(R)-(3-oxo-morpholin-4-yl)-phenyl]-chlorocarbonyl-amino} ethyl ester 
• 1447919-68-7 acetic acid-1-benzyloxymethyl-2-[(R)-4-(3-oxo-morpholin-4-yl)phenylamino]-ethylester 
• 1117893-58-9 4-(4-(R)-3-benzyloxy-2-hydroxy-propylamino)phenyl-morpholin-3-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1446022-14-5 butyric acid-2(R)-2-hydroxy-3-[4-(3-oxo-morpholin-4-yl)phenylamino]-propyl ester 
• 1447919-65-4 4-[4-{(R)-2,3-dihydroxy-propylamino}phenyl]morpholin-3-one 

Downstream Products

• 1117893-61-4 R-(2-oxo-3-((4-(3-oxo-morpholinyl)phenyl)oxazolidin-5-yl))methylmethanesulfonate 
• 366789-02-8 Rivaroxaban 
• 1313613-19-2 4-(4-((S)-5-(tert-butylaminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one 
• 1313613-22-7 4-(4-((S)-5-(tert-octylaminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one 
• 1313613-21-6 5-chloro-N-tert-butyl-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl}thiophene-2-carboxamide 
• 1313613-23-8 5-chloro-N-tert-octyl-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl}thiophene-2-carboxamide 
• 1313613-20-5 4-(4-((S)-5-(tert-butylaminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one methanesulfonic salt 
• 446292-08-6 2-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione 
• 1446022-16-7 (S)-4-(4-(5-(aminomethyl)-2-oxo-oxazolidin-3-yl)phenyl)morpholin-3-one formate salt 
• 1446022-18-9 (S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one L-(+)-mandelate 
• 1424942-80-2 (R)-(2-oxo-3-(4-(3-oxo-morpholino)phenyl)oxazolidin-5-yl)methyl 4-methylbenzene sulfonate 
• 1252018-26-0 4-[4-((R)-5-(iodomethyl)-2-oxo-oxazolidin-3-yl)phenyl]-morpholin-3-one 
• 1251952-73-4 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}-morpholin-3-one p-toluenesulfonic acid salt 
• 1349248-79-8 4-{4-[(5R)-5-(azidomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}-morpholin-3-one 

Relevant articles and documents

Stereocontrolled, Divergent, Al(lll)-Catalyzed Coupling of Chiral N-Aryl Epoxy Amines and CO2

A divergent coupling reaction was achieved between N-aryl epoxy amines and CO2. By using two different cocatalysts, tetrabutylammonium iodide (TBAI) or 4-dimethylaminopyridine (DMAP) together with an Al(III) Lewis acid, cyclic carbonates or oxazolidinones were selectively produced through two distinct reaction pathways, respectively. The proposed reaction mechanism was supported by the stereochemical determination of the products. A gram-scale production of Linezolid was successfully achieved.

PROCESSES AND INTERMEDIATES FOR PREPARING RIVAROXABAN

The invention discloses processes for the preparation of rivaroxaban and its pharmaceutically acceptable salts, solvates, and hydrates thereof. The invention also relates to novel intermediates for the preparation of rivaroxaban.

PROCESSES AND INTERMEDIATES FOR PREPARING RIVAROXABAN

The invention discloses processes for the preparation of rivaroxaban and its pharmaceutically acceptable salts, solvates, and hydrates thereof. The invention also relates to novel intermediates for the preparation of rivaroxaban.