111795-28-9

Basic information

• Product Name: Benzeneacetic acid, a-(1-methylpropylidene)-, (E)-
• CAS NO: 111795-28-9
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol File: 111795-28-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-(1-methylpropylidene)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-(1-methylpropylidene)-, (E)-(111795-28-9)
• EPA Substance Registry System: Benzeneacetic acid, a-(1-methylpropylidene)-, (E)-(111795-28-9)

Safety Data

• Hazardous Substances Data: 111795-28-9(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 622-76-4 1-phenyl-1-butyne 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 111795-29-0 (2S,3S)-3-Methyl-2-phenyl-pentanoic acid 
• 121251-94-3 (2S,3R)-3-Methyl-2-phenyl-pentanoic acid 
• 201346-27-2 (2R,3S)-3-Methyl-2-phenyl-pentanoic acid 

Relevant articles and documents

Synthesis of Trisubstituted Acrylic Acids through Nickel-Catalyzed Carbomagnesiation of Alkynes and Carbon Dioxide Fixation

A nickel-catalyzed synthesis of trisubstituted acrylic acids from alkynes, Grignard reagents, and CO2 is reported. The reaction proceeds through carbomagnesiation of the alkyne with Grignard reagent followed by carboxylation with CO2 under mild reaction conditions in short time. Various unsymmetrical alkynes were transformed into the corresponding acid products in good yields with high stereoselectivity.