111822-69-6 Usage
Description
(R)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BI-2-naphthol, also known as a chiral binaphthol, is an organic compound characterized by its white powder form. It features a unique chiral center, which makes it a valuable building block in the synthesis of various chiral molecules. Its distinctive structure allows it to form rare earth metal complexes and act as a precursor to a chiral Br?nsted acid, both of which are utilized in catalyzing enantioselective reactions.
Uses
Used in Pharmaceutical Industry:
(R)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BI-2-naphthol serves as a precursor to a chiral Br?nsted acid (CAS 674745), which is employed as a catalyst for enantioselective aza Diels-Alder reactions. This reaction is crucial in the synthesis of complex bicyclic lactams, which are valuable chiral building blocks in the development of pharmaceuticals with potential therapeutic applications.
Used in Catalyst Industry:
The chiral binaphthol is also utilized in the formation of rare earth metal complexes, which act as catalysts for intramolecular hydroamination of amino olefins. This catalytic process leads to the production of chiral pyrrolidines, important intermediates in the synthesis of biologically active compounds and other specialty chemicals.
These applications highlight the significance of (R)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BI-2-naphthol in the fields of pharmaceuticals and catalysis, where its unique properties contribute to the development of enantioselective synthetic routes and the production of valuable chiral compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 111822-69-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,8,2 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 111822-69:
(8*1)+(7*1)+(6*1)+(5*8)+(4*2)+(3*2)+(2*6)+(1*9)=96
96 % 10 = 6
So 111822-69-6 is a valid CAS Registry Number.