111863-97-9Relevant articles and documents
The Significance of the Diphosphate Linkage Involved in the Substrates for Prenyltransferase. Geranyl- and Dimethylallyl Methylenediphosphonate as Artificial Substrates
Gotoh, Takeshi,Koyama, Tanetoshi,Ogura, Kyozo
, p. 1627 - 1630 (1987)
Dimethylallyl- and geranyl methylenediphosphonate are active as artificial substrates for farnesyl diphosphate synthase to give E,E-farnesyl diphosphate.By comparing the kinetic data obtained with the analogues and the natural substrates, the significance of the diphosphate moiety of the substrates of prenyltransferase is discussed.