1118750-09-6Relevant articles and documents
Sn-free Ni-catalyzed reductive coupling of glycosyl bromides with activated alkenes
Gong, Hegui,Andrews, R. Stephen,Zuccarello, Joseph L.,Lee, Stephen J.,Gagne, Michel R.
supporting information; experimental part, p. 879 - 882 (2009/07/25)
A mild, stereoselective method for the Ni-catalyzed synthesis of α-C-alkylglycosides is reported. This approach entails the reductive coupling of glycosyl bromides with activated alkenes at room temperature, with low alkene loading as an important feature. Diastereoselective coupling with 2-substituted acrylate derivatives was made possible through the use of 2,4-dimethyl-3-pentanol as a proton source.