112017-99-9

Basic information

• Product Name: IBUPROFENPICONOL
• Synonyms: Unii-B0F91K5U4n;pyridin-2-ylMethyl 2-(4-isobutylphenyl)propanoate
• CAS NO: 112017-99-9
• Molecular Formula: C19H23NO2
• Molecular Weight: 297.396
• EINECS: 264-979-8
• Mol File: 112017-99-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: IBUPROFENPICONOL(CAS DataBase Reference)
• NIST Chemistry Reference: IBUPROFENPICONOL(112017-99-9)
• EPA Substance Registry System: IBUPROFENPICONOL(112017-99-9)

Safety Data

• Hazardous Substances Data: 112017-99-9(Hazardous Substances Data)

Usage

General Description

Ibuprofenpiconol is a compound that contains both ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and piconol, a local anaesthetic. This combination is primarily used in the form of a topical gel for the treatment of musculoskeletal and joint pain, such as arthritis, strains, and sprains. Ibuprofenpiconol works by reducing inflammation and pain in the affected area, while the local anaesthetic provides relief by numbing the nerves. This combination allows for both immediate pain relief and long-term reduction of inflammation, making it an effective option for managing various types of localized pain. Ibuprofenpiconol is generally well-tolerated and is available over-the-counter in many countries for easy access to pain relief.

InChI:InChI=1/C19H23NO2/c1-14(2)12-16-7-9-17(10-8-16)15(3)19(21)22-13-18-6-4-5-11-20-18/h4-11,14-15H,12-13H2,1-3H3

Upstream product

• 586-98-1 2-Hydroxymethylpyridine 
• 61566-34-5 (+/-)-ibuprofen methyl ester 
• 71381-91-4 (+/-)-2-(4-isobutylphenyl)propanoyl chloride 
• 15687-27-1 ibuprofen 
• 2387-23-7 1,3-Dicyclohexylurea 

Relevant articles and documents

A green chemistry approach to ibuprofen piconol

Ibuprofen piconol synthesis has been described. The use of solid catalyst has demonstrated green chemistry approach with promoted atom economy of 94% compared to the reported 68%.

Method for producing ester group-containing compound being useful for optical material applications such as optical compensation films

The present invention provides a novel method for producing an ester group-containing compound and a derivative produced by using the compound as a synthetic intermediate. The present invention also provides a polymerizable composition containing the compound obtained by the production method and a film-shaped polymer obtained by polymerizing the polymerizable composition. The present invention is a method for producing an ester group-containing compound, the method including a mixing step of mixing a condensing agent, a Bronsted acid, carboxylic acid, and phenol or alcohol to prepare a reaction mixture. The Bronsted acid is selected from anything other than the condensing agent, the carboxylic acid, and the phenol.

Alterntnate routes for the synthesis of ibuprofen piconol

New, improved and alternate methods for the synthesis of ibuprofen piconol from ibuprofen and pyridine-2-methanol have been demonstrated with different carboxyl activating groups.