112031-18-2 Usage
Description
Tetradecanoic acid, 3-(phenylmethoxy)-, methyl ester, (S)is a chemical compound with the molecular formula C21H32O3. It is an ester derived from tetradecanoic acid, featuring a phenylmethoxy group at the 3rd carbon and a methyl ester group. Tetradecanoic acid, 3-(phenylmethoxy)-, methyl ester, (S)is characterized by its aromatic and ester functional groups, which contribute to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
Tetradecanoic acid, 3-(phenylmethoxy)-, methyl ester, (S)is used as an intermediate for the synthesis of (R,S,S,S)-Orlistat (O686480), which is an isomeric impurity of Orlistat (O686500). Orlistat is a medication used to aid in weight loss and is known for its modulatory activity on endocannabinoid 2-arachidonoylglycerol metabolism. The synthesis of this compound is crucial for the development of pharmaceuticals targeting weight management and metabolic regulation.
Check Digit Verification of cas no
The CAS Registry Mumber 112031-18-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,0,3 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 112031-18:
(8*1)+(7*1)+(6*2)+(5*0)+(4*3)+(3*1)+(2*1)+(1*8)=52
52 % 10 = 2
So 112031-18-2 is a valid CAS Registry Number.
112031-18-2Relevant articles and documents
Asymmetric synthesis of tetrahydrolipstatin and valilactone
Case-Green, Stephen C.,Davies, Stephen G.,Roberts, Paul M.,Russell, Angela J.,Thomson, James E.
experimental part, p. 2620 - 2631 (2009/04/06)
The highly diastereoselective aldol reaction between acyl complexes of the iron chiral auxiliary [(η5-C5H5)Fe(CO)(PPh3)] and β-hydroxy aldehydes (obtained via a Noyori asymmetric hydrogenation), followed by a tandem oxidative decomplexation-cyclisation process gives access to β-substituted and α,β-disubstituted β-lactones in high ee. This methodology has been employed in the asymmetric syntheses of tetrahydrolipstatin and valilactone.
A Convenient Benzylation Procedure for β-Hydroxy Esters
Widmer, Ulrich
, p. 568 - 570 (2007/10/02)
Benzylation of β-hydroxy esters, containing primary and secondary alcohol functions, with benzyl 2,2,2-trichloroacetimidate gives the corresponding benzyl ethers in good yield.In the case of chiral substrates no racemisation is observed.
