1121-25-1 Usage
Description
3-Hydroxy-2-methylpyridine is an organic compound with the chemical formula C6H7NO. It is a beige-brown powder and is a derivative of Vitamin B6, which plays a crucial role in various biochemical processes in the human body. 3-Hydroxy-2-methylpyridine is also utilized in the synthesis of other chemical compounds, particularly those belonging to the pyridine and pyrimidine families.
Uses
Used in Pharmaceutical Industry:
3-Hydroxy-2-methylpyridine is used as a key intermediate in the synthesis of various substituted pyridine and pyrimidine derivatives. These derivatives are essential in the development of medications for treating viral infections, making this compound a valuable component in the pharmaceutical sector.
Used in Chemical Synthesis:
In the field of organic chemistry, 3-Hydroxy-2-methylpyridine serves as a vital building block for the creation of more complex molecules, particularly those within the pyrimidine family. Its unique structure allows for further functionalization and modification, enabling the development of novel compounds with potential applications in various industries.
Used in Vitamin B6 Derivatives:
As an active derivative of Vitamin B6, 3-Hydroxy-2-methylpyridine plays a significant role in the production of Vitamin B6 supplements and related products. Vitamin B6 is essential for various bodily functions, including the synthesis of neurotransmitters, hemoglobin, and immune system support. The compound's involvement in this process highlights its importance in the nutritional and healthcare industries.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 2969, 1949 DOI: 10.1021/ja01177a007
Check Digit Verification of cas no
The CAS Registry Mumber 1121-25-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,2 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1121-25:
(6*1)+(5*1)+(4*2)+(3*1)+(2*2)+(1*5)=31
31 % 10 = 1
So 1121-25-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NO/c1-5-6(8)3-2-4-7-5/h2-4,8H,1H3
1121-25-1Relevant articles and documents
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Chien,Cheng
, p. 867,869 (1970)
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Conversion of 5-hydroxymethylfurfural into 6-(hydroxymethyl)pyridin-3-ol: A pathway for the formation of pyridin-3-ols in honey and model systems
Hidalgo, Francisco J.,Lavado-Tena, Cristina M.,Zamora, Rosario
, p. 5448 - 5454 (2020/06/08)
The formation of 6-(hydroxymethyl)pyridin-3-ol by ring expansion of 5-(hydroxymethyl)furfural (HMF) in the presence of ammonia-producing compounds was studied to determine the routes of formation of pyridin-3-ols in foods. 6-(Hydroxymethyl)pyridin-3-ol was produced from HMF in model systems, mostly at neutral pH values, as a function of reaction times and temperature and with an activation energy (Ea) of 74 ± 3 kJ/mol, which was higher than that of HMF disappearance (43 ± 4 kJ/mol). A reaction pathway is proposed, which is general for the formation of pyridin-3-ols from 2-oxofurans. Thus, it explains the conversions of furfural into pyridin-3-ol and of 2-acetylfuran into 2-methylpyridin-3-ol, which were also studied. When honey and sugarcane honey were heated, they produced different pyridin-3-ols, although 6-(hydroxymethyl)pyridin-3-ol was the pyridine-3-ol produced to the highest extent. Obtained results suggest that formation of pyridin-3-ols in foods is unavoidable when 2-oxofurans are submitted to thermal heating and ammonia (or ammonia-producing compounds) is present.
A facile synthesis of 1,6-dideoxynojirimycin from l-sorbose
An, Jia-Ning,Meng, Xiang-Bao,Yao, Yun,Li, Zhong-Jun
, p. 2200 - 2203 (2007/10/03)
A practical synthesis of 1,6-dideoxynojirimycin, a potent glycosidase inhibitor, starting from l-sorbose, is described.
An efficient facile and selective hydroxylation of nitrogen heterocycles
Nasreen, Aayesha,Adapa, Srinivas R.
, p. 501 - 506 (2007/10/03)
Nitrogen heterocycles have been efficiently hydroxylated under mild and neutral conditions by employing Cupric nitrate/phosphate buffer/30%hydrogen peroxide system. The present method afforded the biologically active and important hydroxy heterocycles. Th