112190-24-6

Basic information

• Product Name: (2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-{[(2S)-3-(1H-imidazol-5-yl)-2-{[(naphthalen-1-yloxy)acetyl]amino}propanoyl]amino}-2-(1-methylethyl)-N-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}hexanamide (non-preferred name)
• CAS NO: 112190-24-6
• Molecular Formula: C₄₅H₆₁N₇O₇
• Molecular Weight: 812.0085
• Mol File: 112190-24-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 1158.5°C at 760 mmHg
• Flash Point: 654.4°C
• Density: 1.215g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: (2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-{[(2S)-3-(1H-imidazol-5-yl)-2-{[(naphthalen-1-yloxy)acetyl]amino}propanoyl]amino}-2-(1-methylethyl)-N-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}hexanamide (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-{[(2S)-3-(1H-imidazol-5-yl)-2-{[(naphthalen-1-yloxy)acetyl]amino}propanoyl]amino}-2-(1-methylethyl)-N-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}hexanamide (non-preferred name)(112190-24-6)
• EPA Substance Registry System: (2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-{[(2S)-3-(1H-imidazol-5-yl)-2-{[(naphthalen-1-yloxy)acetyl]amino}propanoyl]amino}-2-(1-methylethyl)-N-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}hexanamide (non-preferred name)(112190-24-6)

Safety Data

• Hazardous Substances Data: 112190-24-6(Hazardous Substances Data)

Usage

Description

(2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[(2S)-3-(1H-imidazol-5-yl)-2-[(naphthalen-1-yloxy)acetyl]aminopropanoyl]amino-2-(1-methylethyl)-N-(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butylhexanamide (non-preferred name) is a complex peptide-like compound with a highly specific and intricate chemical structure. It features multiple stereocenters and functional groups, such as hydroxyl, amine, and carbonyl groups, which may contribute to its potential biological activity and therapeutic applications.

Uses

Used in Pharmaceutical Industry:
(2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[(2S)-3-(1H-imidazol-5-yl)-2-[(naphthalen-1-yloxy)acetyl]aminopropanoyl]amino-2-(1-methylethyl)-N-(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butylhexanamide (non-preferred name) is used as a potential therapeutic agent for targeting specific receptors or biological pathways due to its complex structure and multiple stereocenters, which may allow for precise interactions with biological targets.

Upstream product

• 117997-58-7 tert-butyl (4S,5R)-4-(cyclohexylmethyl)-5-formyl-2,2-dimethyl-3-oxazolidinecarboxylate 
• 107599-99-5 (4R,5S)-(+)-3-[3-methyl-1-oxobut-1-yl]-4-methyl-5-phenyl-2-oxazolidinone 
• 112190-42-8 3-<3(R)-<3-(tert-butyloxycarbonyl)-4(S)-cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-3-hydroxy-2(R)-isopropyl-1-oxopropyl>-4(R)-methyl-5(S)-phenyl-2-oxazolidinone 
• 134527-83-6 1(R)-<3-(tert-butyloxycarbonyl)-4(S)-(cyclohexylmethyl)-2,2-dimethyl-5(R)-oxazolidinyl>-2(S)-isopropyl-1,3-propanediol 
• 146394-88-9 (2R,3R,4R,5S)-5-Amino-6-cyclohexyl-3,4-dihydroxy-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 112190-45-1 2(R)-<5(R)-<1(S)-<(tert-butyloxycarbonyl)amino>-2-cyclohexylethyl>-2,2-dimethyl-4(R)-dioxolanyl>-3-methylbutanoic acid 

Relevant articles and documents

Inhibitors of the Protease from Human Immunodeficiency Virus: Design and Modeling of a Compound Containing a Dihydroxyethylene Isostere Insert with High Binding Affinity and Effective Antiviral Activity

The peptidomimetic template and the dihydroxyethylene isostere insert that were applied successfully to the design of renin inhibitors have been extended to the related protease from human immunodeficiency virus (HIV).The present report describes the stru