1122-35-6Relevant articles and documents
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Filimonov et al.
, (1979)
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One-step RhCl3-catalyzed deprotection of acyclic N-allyl amides
Zacuto, Michael J.,Xu, Feng
, p. 6298 - 6300 (2007)
(Chemical Equation Presented) A convenient one-step RhCl 3-catalyzed deprotection of acyclic N-allyl amides is described. Preliminary mechanistic studies reveal that the key to the success of the one-step deprotection process is the dual function of RhCl3 in alcohol solvents. Reaction of RhCl3 with n-PrOH not only provides an active rhodium hydride species to catalyze isomerization of N-allyl amides to corresponding enamides but also generates a crucial catalytic amount of HCl to convert the enamides to deallylated amides through N,O-acetal exchange.
XtalFluor-E mediated proto-functionalization of: N -vinyl amides: Access to N -acetyl N, O -acetals
Yi,Gholami,Morrow,Borhan
supporting information, p. 9570 - 9574 (2017/11/30)
XtalFluor-E has been extensively used in a broad range of reactions in the past few years. Here we report its use with protic nucleophiles in a catalytic manner for the in situ generation of protons that lead to the proto-functionalization of activated ol
TFA-catalyzed C-N bond activation of enamides with indoles: Efficient synthesis of 3,3-bisindolylpropanoates and other bisindolylalkanes
Xu, Hai-Yan,Zi, You,Xu, Xiao-Ping,Wang, Shun-Yi,Ji, Shun-Jun
, p. 1600 - 1605 (2013/02/25)
An efficient TFA-catalyzed cleavage of C-N bonds in alkylation of indoles by tertiary enamides was described. A variety of bisindolylalkane derivatives, especially 3,3-bisindolylpropanoates, were expeditiously synthesized in good yields.