112204-58-7

Basic information

• Product Name: 5-Bromo-2-fluorophenol
• Synonyms: 2-FLUORO-5-BROMOPHENOL;5-BROMO-2-FLUOROPHENOL;3-Bromo-6-fluorophenol;5-Bromo-2-fluorophenol 98%;5-Bromo-2-fluorophenol98%;5-Bromo-2-fluorophen;5 - broMine phenol - 2 - fluorine;Fluoro-5-bromophenol
• CAS NO: 112204-58-7
• Molecular Formula: C₆H₄BrFO
• Molecular Weight: 191
• EINECS: 207-168-6
• Product Categories: Aromatic Phenols;Phenol&Thiophenol&Mercaptan;Fluorobenzene;Fluorine series
• Mol File: 112204-58-7.mol
• Article Data: 13

Chemical Properties

• Melting Point: 60-80 °C
• Boiling Point: 53℃/0.2mm
• Flash Point: 78.2 °C
• Appearance: Off-white/Crystalline
• Density: 1.511 g/cm³
• Vapor Pressure: 0.176mmHg at 25°C
• Refractive Index: 1.5630-1.5670
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.74±0.10(Predicted)
• CAS DataBase Reference: 5-Bromo-2-fluorophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-fluorophenol(112204-58-7)
• EPA Substance Registry System: 5-Bromo-2-fluorophenol(112204-58-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 112204-58-7(Hazardous Substances Data)

Usage

Description

5-Bromo-2-fluorophenol is an organic compound characterized by the presence of a bromine atom at the 5th position and a fluorine atom at the 2nd position on a phenol molecule. It exhibits chemical properties typical of phenols, with a colorless to light yellow liquid appearance.

Uses

Used in Pesticide Industry:
5-Bromo-2-fluorophenol is used as a reactant for the preparation of 1-aryl-1-(3-arylpropyl and -propenyl)cyclopropane derivatives, which are employed as insecticides. These derivatives are synthesized to target and control various insect pests, leveraging the unique structural features of 5-Bromo-2-fluorophenol to enhance the effectiveness and selectivity of the resulting insecticidal compounds.

InChI:InChI=1/C6H4BrF2N/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,10H2

Upstream product

• 112204-57-6 dihydroxy-(5-bromo-2-fluorophenyl)-borane 
• 103291-07-2 4-bromo-1-fluoro-2-methoxy-benzene 
• 348-61-8 1-bromo-3,4-difluorobenzene 
• 92545-83-0 2-(3-bromophenoxy)pyridine 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 942069-51-4 2-(5-bromo-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 900174-64-3 4-Bromo-2-ethoxy-1-fluorobenzene 
• 112204-59-8 5-bromo-2-fluorophenyl phenyl ether 
• 944278-95-9 5-bromo-2-fluoro-1-(isopropyloxy)benzene 
• 954235-78-0 (3-bromo-6-fluorophenyl)difluoromethyl ether 
• 1392196-69-8 (5-bromo-2-fluoro-phenoxy)-tert-butyl-dimethyl-silane 
• 103291-07-2 4-bromo-1-fluoro-2-methoxy-benzene 
• 1036724-54-5 2-(benzyloxy)-4-bromo-1-fluorobenzene 
• 861928-19-0 4,5-dibromo-2-fluoroanisole 
• 865186-62-5 2-bromo-4-fluoro-5-methoxylbenzaldehyde 
• 1421503-38-9 4-bromo-5-ethyl-2-fluoro-phenol 

Relevant articles and documents

C-H activation/borylation/oxidation: A one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups

An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses. Copyright

BENZAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS

The present invention provides novel benzamide derivatives of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, W, Y, Z, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.

TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS

A quinazoline derivative of formula (I), or a pharmaceutically acceptable salt thereof: formula (I) for use in treatment of prevention of a flaviviridae infection.