112233-23-5 Usage
Description
5,6-Dihydro-3-(MethylaMino)-2H-1,4-thiazin-2-one OxiMe Hydrochloride, also known as Ranitidine EP Impurity G, is a chemical compound that is identified as an impurity in Ranitidine HCl (R120000). It is characterized by its unique chemical structure and properties, which differentiate it from the main compound.
Used in Pharmaceutical Industry:
5,6-Dihydro-3-(MethylaMino)-2H-1,4-thiazin-2-one OxiMe Hydrochloride is used as an impurity in Ranitidine HCl (R120000) for the purpose of quality control and assurance in the manufacturing process. The presence of this impurity is monitored and controlled to ensure the safety, efficacy, and purity of the final pharmaceutical product.
Check Digit Verification of cas no
The CAS Registry Mumber 112233-23-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,2,3 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 112233-23:
(8*1)+(7*1)+(6*2)+(5*2)+(4*3)+(3*3)+(2*2)+(1*3)=65
65 % 10 = 5
So 112233-23-5 is a valid CAS Registry Number.
112233-23-5Relevant articles and documents
Isolation and Identification of the Hydrolytic Degradation Products of Ranitidine Hydrochloride
Haywood, Phillip A.,Martin-Smith, Michael,Cholerton, Trevor J.,Evans, Michael B.
, p. 951 - 954 (2007/10/02)
Hydrolytic degradative studies on ranitidine hydrochloride (1) have shown that two different pathways are operative under strongly acid and strongly alkaline conditions.At intermediate pH values both pathways are operative whilst at very low pH values ranitidine hydrochloride is resistant to hydrolytic cleavage.This resistance to hydrolysis may be ascribed to C- protonation of the enediamine.
