112245-59-7

Basic information

• Product Name: METHYL-3,5-O-ISOPROPYLIDENE-D-XYLOFURANOSE
• Synonyms: METHYL-3,5-O-ISOPROPYLIDENE-D-XYLOFURANOSE;D-Methyl 3,5-O-isopropylidene-xylofuranoside
• CAS NO: 112245-59-7
• Molecular Formula: C₉H₁₆O₅
• Molecular Weight: 204.22
• Mol File: 112245-59-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL-3,5-O-ISOPROPYLIDENE-D-XYLOFURANOSE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-3,5-O-ISOPROPYLIDENE-D-XYLOFURANOSE(112245-59-7)
• EPA Substance Registry System: METHYL-3,5-O-ISOPROPYLIDENE-D-XYLOFURANOSE(112245-59-7)

Safety Data

• Hazardous Substances Data: 112245-59-7(Hazardous Substances Data)

Upstream product

• 58-86-6 D-xylose 
• 67-56-1 methanol 
• 67-64-1 acetone 
• 532-20-7 D-xylofuranose 
• 1824-96-0 methyl xylofuranoside 

Downstream Products

• 114071-59-9 methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-threo-pentofuranoside 
• 114071-60-2 methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-β-D-threo-pentofuranoside 
• 66323-40-8 alpha-3'-azido-2',3'-dideoxythymidine 
• 791084-51-0 methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside 
• 114071-61-3 Trifluoro-methanesulfonic acid (2R,3R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-tetrahydro-furan-3-yl ester 
• 133908-22-2 methyl 3-azido-5-O-tert-butyldiphenylsilyl-2,3-dideoxy-α,β-D-erythor-pentofuranoside 
• 30516-87-1 3'-azido-2',3'-deoxythymidine 
• 116390-97-7 Methanesulfonic acid (2R,3R)-5-methoxy-2-trityloxymethyl-tetrahydro-furan-3-yl ester 
• 532413-72-2 methyl 3-azido-2,3-dideoxy-5-O-triphenylmethyl-D-erythro-pentofuranoside 
• 16801-99-3 (2R,3R)-5-Methoxy-2-trityloxymethyl-tetrahydro-furan-3-ol 

Relevant articles and documents

MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF

The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.

METHYL 5-O-TERT-BUTYLDIPHENYLSILYL-2-DEOXY-D-THREO-PENTOFURANOSIDE; AN APPROACH TO THE SYNTHESIS OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES INCLUDING 3'-AZIDO-3'-DEOXYTHYMIDINE AND OF 3'-SUBSTITUTED-2',3'-DIDEOXY-C-NUCLEOSIDES

The Barton deoxygenation of methyl 3,5-O-isopropylidene-αβ-D-xylofuranoside is the key step in a short synthesis of methyl 5-O-tert-butyldiphenylsilyl-2-deoxy-αβ-D-threo-pentofuranoside (1) from D-xylose.The syntheses of methyl 2,3-dideoxy-3-fluoro-αβ-D-erythro-pentofuranoside and of a protected 3-azido-2,3-dideoxy-D-erythro-pentofuranose, a possible intermediate for the synthesis of 3'-azido-3'-deoxythymidine (AZT), are reported and the potential of (1) as a divergent intermediate for the preparation of 3'-substituted-2',3'-dideoxynucleosides and C-nucleoside analogues is discussed.