112279-72-8

Basic information

• Product Name: 4-BROMO-2,3-DIFLUOROANILINE
• Synonyms: 4-Bromo-2,3-difluoroaniline 97%
• CAS NO: 112279-72-8
• Molecular Formula: C₆H₄BrF₂N
• Molecular Weight: 208.01
• Mol File: 112279-72-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 215.1±35.0℃ (760 Torr)
• Flash Point: 83.9±25.9℃
• Appearance: /
• Density: 1.788±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.15mmHg at 25°C
• Refractive Index: 1.57
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.48±0.10(Predicted)
• CAS DataBase Reference: 4-BROMO-2,3-DIFLUOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2,3-DIFLUOROANILINE(112279-72-8)
• EPA Substance Registry System: 4-BROMO-2,3-DIFLUOROANILINE(112279-72-8)

Safety Data

• Hazardous Substances Data: 112279-72-8(Hazardous Substances Data)

Usage

General Description

4-Bromo-2,3-difluoroaniline is a chemical compound with the molecular formula C6H4BrF2N. It is a derivative of aniline and is commonly used in the synthesis of other organic compounds. This chemical is identified by its two bromine atoms and two fluorine atoms attached to the aromatic ring, giving it unique chemical and physical properties. 4-Bromo-2,3-difluoroaniline is used in the production of pharmaceuticals, agrochemicals, and dyes, and it is also employed as an intermediate in the manufacturing of various organic compounds. Due to its potential reactivity and toxicity, it requires careful handling and proper storage to prevent any adverse effects on human health and the environment.

InChI:InChI=1/C6H4BrF2N/c7-3-1-2-4(10)6(9)5(3)8/h1-2H,10H2

Upstream product

• 4519-40-8 2,3-difluoroanilline 

Downstream Products

• 1112969-31-9 C₁₄H₁₀BrF₂NO₂ 
• 1112969-33-1 C₁₅H₁₇BrF₂N₂O₄ 
• 1112969-32-0 C₁₀H₈BrF₂NO₃ 
• 1373920-77-4 6-chloro-2,3-difluoroaniline 

Relevant articles and documents

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OXADIAZOLE DERIVATIVE HAVING ENDOTHELIAL LIPASE INHIBITORY ACTIVITY

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is aromatic carbocycle or aromatic heterocycle,Z is —NR5—, —O— or —S—,R5 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl or the like,R1 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like,R2 and R3 are each independently hydrogen, halogen, hydroxy or the like,R4 is a group represented by the formula: —(CR6R7)n-R8, wherein R6 and R7 are each independently hydrogen, halogen, hydroxy or the like, n is an integer of 0 to 3, R8 is carboxy, cyano, substituted or unsubstituted alkyl or the like, Rx is halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like,m is an integer of 0 to 3.

Methods and Processes For Syntheses and Manufacture of Antimicrobial 1(Ortho-Fluorophenyl)dihydropyridones

Provided herein are methods and processes for synthesis and manufacture of compounds of formula I: or its crystal forms, pharmaceutical acceptable salts, prodrugs, hydrates, or solvates thereof.