1123512-36-6

Basic information

• Product Name: 1-(4-((5-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)-amino)benzyl)piperidine-4-carboxylic acid
• Synonyms: 1-(4-((5-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)-amino)benzyl)piperidine-4-carboxylic acid
• CAS NO: 1123512-36-6
• Molecular Weight: 454.476
• Mol File: 1123512-36-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-((5-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)-amino)benzyl)piperidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-((5-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)-amino)benzyl)piperidine-4-carboxylic acid(1123512-36-6)
• EPA Substance Registry System: 1-(4-((5-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)-amino)benzyl)piperidine-4-carboxylic acid(1123512-36-6)

Safety Data

• Hazardous Substances Data: 1123512-36-6(Hazardous Substances Data)

Upstream product

• 887757-48-4 2-(4-(difluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 5905-69-1 1-bromo-4-(difluoromethoxy)benzene 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 2971-79-1 isonipecotic acid methyl ester 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 1123922-57-5 1-(4-(5-bromopyrimidin-2-ylamino)benzyl)piperidine-4-carboxylic acid 

Relevant articles and documents

Exemplifying Prediction of Preferred Coupling Partners in Developing a Buchwald-Hartwig Coupling for the Synthesis of a c-Kit Inhibitor

Two convergent syntheses for compound 1 are described that apply Buchwald-Hartwig coupling as the key step. This development work provides a direct comparison of the coupling results from different coupling partners and illustrates that more efficiency ca