1123622-35-4

Basic information

• Product Name: 4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]benzaldehyde
• Synonyms: 4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]benzaldehyde
• CAS NO: 1123622-35-4
• Molecular Weight: 350.371
• Mol File: 1123622-35-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]benzaldehyde(1123622-35-4)
• EPA Substance Registry System: 4-[(1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dienyl]benzaldehyde(1123622-35-4)

Safety Data

• Hazardous Substances Data: 1123622-35-4(Hazardous Substances Data)

Upstream product

• 1924-25-0 (5E)-6-(4-hydroxy-3-methoxyphenyl)hex-5-ene-2,4-dione 
• 623-27-8 terephthalaldehyde, 

Relevant articles and documents

Synthesis and biological evaluation of curcuminoid pyrazoles as new therapeutic agents in inflammatory bowel disease: Effect on matrix metalloproteinases

Seven N-unsubstituted curcuminoid pyrazoles have been synthesized from the corresponding β-diketones (including curcumin). We evaluated the possibility of curcuminoid pyrazoles regulating the activity of matrix metalloproteinases (MMPs) by human intestinal epithelial cells in vitro. Zymographic analysis revealed that three compounds significantly down-regulated MMP-9 activity on inflammation-induced intestinal epithelial cells, making them original candidates for the treatment of inflammatory bowel disease (IBD).