1123661-07-3

Basic information

• Product Name: 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)-2-hydroxybenzamide trifluoroacetate
• Synonyms: 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)-2-hydroxybenzamide trifluoroacetate
• CAS NO: 1123661-07-3
• Molecular Weight: 358.317
• Mol File: 1123661-07-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)-2-hydroxybenzamide trifluoroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)-2-hydroxybenzamide trifluoroacetate(1123661-07-3)
• EPA Substance Registry System: 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)-2-hydroxybenzamide trifluoroacetate(1123661-07-3)

Safety Data

• Hazardous Substances Data: 1123661-07-3(Hazardous Substances Data)

Upstream product

• 862992-92-5 2-benzyloxy-3-bromo-benzamide 
• 900503-08-4 3-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylic acid tert-butyl ester 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 1123661-10-8 3-endo-(8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate 

Relevant articles and documents

8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists

The invention provides 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds of formula (I): wherein R2, R7, and m are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.