112391-90-9

Basic information

• Product Name: Acetamide, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-imino-2-[[[ (phenylmethyl)amino]sulfonyl]amino]-
• CAS NO: 112391-90-9
• Molecular Formula: C19H27N5O4S2
• Mol File: 112391-90-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-imino-2-[[[ (phenylmethyl)amino]sulfonyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-imino-2-[[[ (phenylmethyl)amino]sulfonyl]amino]-(112391-90-9)
• EPA Substance Registry System: Acetamide, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-imino-2-[[[ (phenylmethyl)amino]sulfonyl]amino]-(112391-90-9)

Safety Data

• Hazardous Substances Data: 112391-90-9(Hazardous Substances Data)

Upstream product

• 66356-53-4 5-{[(2-aminoethyl)thio]methyl}-N,N-dimethyl-2-furfurylamine 
• 106350-10-1 4-amino-2-benzyl-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1-dioxide 

Relevant articles and documents

Potential histamine H2-receptor antagonists. Synthesis, conformational studies and activity of novel 3-oxo-1,2,5-thiadiazole 1,1-dioxide derivatives.

New histamine H2-receptor antagonists bearing a novel "urea equivalent", the 3-oxo-1,2,5-thiadiazole 1,1-dioxide ring, have been synthesized in a transamination reaction. Open chain derivatives have also been obtained. Theoretical conformational analysis of the compounds has been carried out using a molecular modelling program. Semiempirical CNDO/2 calculations have also been performed. The antisecretory and cytoprotective activities of the compounds have been evaluated.