1126430-24-7

Basic information

• Product Name: 1-(2-fluoro-4-nitrophenyl)-4-(2-fluoroethyl)piperazine
• Synonyms: 1-(2-fluoro-4-nitrophenyl)-4-(2-fluoroethyl)piperazine
• CAS NO: 1126430-24-7
• Molecular Weight: 271.267
• Mol File: 1126430-24-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2-fluoro-4-nitrophenyl)-4-(2-fluoroethyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-fluoro-4-nitrophenyl)-4-(2-fluoroethyl)piperazine(1126430-24-7)
• EPA Substance Registry System: 1-(2-fluoro-4-nitrophenyl)-4-(2-fluoroethyl)piperazine(1126430-24-7)

Safety Data

• Hazardous Substances Data: 1126430-24-7(Hazardous Substances Data)

Upstream product

• 369-34-6 3,4-difluoronitrobenzene 
• 762-49-2 2-fluoroethyl bromide 
• 154590-33-7 1-(2-fluoro-4-nitrophenyl)piperazine 

Downstream Products

• 1126430-25-8 3-fluoro-4-(4-(2-fluoroethyl)piperazin-1-yl)aniline 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND USES THEREOF

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder, a cancer, a tumor, an inflammatory disease, an autoimmune disease, psoriasis, dry eye or an immunologically related disease, and in some embodiments diseases or disorders related to the dysregulation of kinase such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, FLT3(D835Y), ITK, TEC, TXK, BTK, or JAK, and the respective pathways.

THIAZOLE AND OXAZOLE KINASE INHIBITORS

The present invention provides thiazole and oxazole compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.