112738-68-8

Basic information

• Product Name: Cyclopropanamine, 1-(trifluoromethyl)- (9CI)
• Synonyms: Cyclopropanamine, 1-(trifluoromethyl)- (9CI);1-TrifluoroMethyl-1-cyclopropylaMine;1-(Trifluoromethyl)cyclopropan-1-amine
• CAS NO: 112738-68-8
• Molecular Formula: C4H6F3N
• Molecular Weight: 125.0923496
• Product Categories: AMINEPRIMARY
• Mol File: 112738-68-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 48.554 °C at 760 mmHg
• Flash Point: -6.494 °C
• Appearance: /
• Density: 1.355 g/cm³
• PKA: 4.59±0.20(Predicted)
• CAS DataBase Reference: Cyclopropanamine, 1-(trifluoromethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanamine, 1-(trifluoromethyl)- (9CI)(112738-68-8)
• EPA Substance Registry System: Cyclopropanamine, 1-(trifluoromethyl)- (9CI)(112738-68-8)

Safety Data

• Hazardous Substances Data: 112738-68-8(Hazardous Substances Data)

Usage

Description

Cyclopropanamine, 1-(trifluoromethyl)(9CI) is an organic compound characterized by its unique molecular structure, which features a cyclopropane ring with an amine group and a trifluoromethyl group attached. Cyclopropanamine, 1-(trifluoromethyl)(9CI) is known for its potential applications in various industries, particularly in the pharmaceutical sector.

Uses

Used in Pharmaceutical Industry:
Cyclopropanamine, 1-(trifluoromethyl)(9CI) is used as a key intermediate compound for the synthesis of tricyclic pyrazole derivatives. These derivatives are valuable in the treatment of diseases mediated by the cannabinoid CB2 receptor, which plays a crucial role in various physiological processes and has been linked to conditions such as inflammation, pain, and neurodegenerative disorders.
The application of Cyclopropanamine, 1-(trifluoromethyl)(9CI) in the pharmaceutical industry is primarily due to its ability to contribute to the development of novel therapeutic agents targeting the cannabinoid CB2 receptor. By modulating the activity of this receptor, the resulting tricyclic pyrazole derivatives have the potential to provide effective treatment options for a range of diseases and conditions.

Upstream product

• 902494-31-9 tert-butyl (1-(trifluoromethyl)cyclopropyl)carbamate 

Downstream Products

• 1572513-19-9 C₁₈H₁₆F₄N₂O₃S 

Relevant articles and documents

THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS

Provided herein are compounds, preferably thyroid hormone receptor beta (THR beta) agonist compounds, compositions thereof, and methods of their preparation, and methods of agonizing THR beta and methods for treating disorders mediated by THR beta.