112779-14-3Relevant articles and documents
1-tert-butyl-5-amino-4-pyrazol-1, 3, 4-oxadiazole thioether compounds and application thereof
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Paragraph 0017-0019, (2020/09/21)
The invention discloses 1-tert-butyl-5-amino-4-pyrazol-1, 3, 4-oxadiazole thioether compounds. The compounds are characterized in that the structural formula of the 1-tert-butyl-5-amino-4-pyrazol-1, 3, 4-oxadiazole thioether compounds is shown in the specification, and R1 in the formula is an alkyl group, a phenyl group or a substituted phenyl group. On the basis of the structure of the 1-phenyl-5-amino-4-pyrazole bisoxadiazole thioether, a series of 1-tert-butyl-5-amino-4-pyrazolyl-1, 3, 4-oxadiazole oxadiazole thioether compounds are synthesized by taking pyrazol as a raw material and replacing the phenyl group on the 1-position of a pyrazol ring with tert-butyl, and the compounds have good treatment, protection and passivation activity on virus diseases caused by tobacco mosaic virus (TMV) through in-vivo experiments of the compounds. And compared with other compounds of the same kind, the compounds of the invention have better protective activity.
HETEROCYCLIC COMPOUND
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Paragraph 0181; 0347, (2014/06/24)
Provided is a heterocyclic compound having an RORγt inhibitory activity. A compound represented by the formula (I): wherein ring A is an optionally substituted cyclic group, Q is a bond, optionally substituted C1-10 alkylene, optionally substituted C2-10 alkenylene, or optionally substituted C2-10 alkynylene, R1 is a substituent, ring B is a thiazole ring, an isothiazole ring or a dihydrothiazole ring, each of which is optionally further substituted by a substituent in addition to R2, and R2 is an optionally substituted cyclyl-carbonyl-C1-6 alkyl group, an optionally substituted aminocarbonyl-C1-6 alkyl group, an optionally substituted cyclyl-C1-6 alkyl group, an optionally substituted cyclyl-C1-6 alkylamino-carbonyl group, an optionally substituted aminocarbonyl-C2-6 alkenyl group, an optionally substituted C1-6 alkylcarbonylamino-C1-6 alkyl group, an optionally substituted cyclyl-aminocarbonyl group, an optionally substituted cyclyl-carbonyl group or an optionally substituted non-aromatic heterocyclic group, or a salt thereof.
Synthesis and herbicidal activities of a series of di(aminopyrazoly) ketone derivatives
Li, Jun-Fei,Zhu, You-Quan,Wang, Xin,Yang, Hua-Zheng
, p. 749 - 755 (2008/03/29)
(Chemical Equation Presented) In order to obtain new lead compounds with high herbicidal activity, a series of 5-amino pyrazole derivatives were designed and synthesized using a series of relational synthons. Their structures were determined by IR, 1H NMR, and elemental analyses. These compounds were screened for herbicidal activities against rape and barnyard grass. Their structure-activity relationships are discussed.