112790-57-5

Basic information

• Product Name: (S)-2-[(3S,4R)-2-Oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-4-phenyl-azetidin-1-yl]-propionic acid methyl ester
• Synonyms: (S)-2-[(3S,4R)-2-Oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-4-phenyl-azetidin-1-yl]-propionic acid methyl ester
• CAS NO: 112790-57-5
• Molecular Weight: 394.427
• Mol File: 112790-57-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-[(3S,4R)-2-Oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-4-phenyl-azetidin-1-yl]-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[(3S,4R)-2-Oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-4-phenyl-azetidin-1-yl]-propionic acid methyl ester(112790-57-5)
• EPA Substance Registry System: (S)-2-[(3S,4R)-2-Oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-4-phenyl-azetidin-1-yl]-propionic acid methyl ester(112790-57-5)

Safety Data

• Hazardous Substances Data: 112790-57-5(Hazardous Substances Data)

Upstream product

• 123882-32-6 2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetic acid 
• 99333-55-8 2-(4(S)-phenyloxazolidin-2-on-3-yl)acetyl chloride 
• 53933-42-9 2-(benzylidene-amino)-propionic acid methyl ester 
• 108493-67-0 (S)-(4-phenyloxazolidinyl)ketene 
• 395649-41-9 methyl (E)-2-(benzylideneamino)propanoate 

Downstream Products

• 3918-87-4 N-L-phenylalanyl-L-alanine 
• 112674-77-8 (S)-2-[(S)-2-((S)-2-Oxo-4-phenyl-oxazolidin-3-yl)-3-phenyl-propionylamino]-propionic acid 

Relevant articles and documents

Synthesis of optically pure 2-azetidinones having N-dehydroamino acid side-chains

An efficient, three step synthesis of optically pure N-vinyl-2-azetidinones 1 starting from α- or β-amino ester imines has been developed. Stau?dinger reaction between amino ester derived imines and ketene precursors gave 2-azetidinones 2. Enolate formati

New aspects of β-lactam chemistry: β-lactams as chiral building blocks

Recent advances on the new aspects of β-lactam chemistry in which β-lactams are used as chiral building blocks for the synthesis of a variety of α-amino acids, 4α-alkyl-α-aminoacids, oligopeptides, labeled peptides, azetidines, amino alcohols, etc., are reviewed.The topics include new and effective routes to dipeptides via homochiral β-lactams obtained by extremely stereoselective cycloadditions of chiral ketenes to chiral imines, a novel route to labeled peptides through extremely stereoselective and stereospecific reductive cleavage of β-lactams on a palladium catalyst, and new efficient syntheses of α-alkyl-α-amino acids and their peptides by the highly effective asymmetric alkylations of β-lactam lithium enolates followed by hydrogenolysis or Birch reduction.Mechanism of those highly selective unique reactions are discussed.