1128268-02-9 Usage
Description
1H-Pyrazole-4-carboxylic acid, 1-[6-(2-hydroxyphenyl)-2-pyridinyl]-5-(trifluoromethyl)-, ethyl ester is a complex chemical compound characterized by a pyrazole core, an ethyl ester functional group, and a trifluoromethyl substituent. It also incorporates a phenyl and pyridinyl ring, with a hydroxy group attached to the phenyl ring. 1H-Pyrazole-4-carboxylic acid, 1-[6-(2-hydroxyphenyl)-2-pyridinyl]-5-(trifluoromethyl)-, ethyl ester's structural features suggest potential applications in the pharmaceutical or agrochemical industries, where its biological activity or reactivity could be leveraged. The presence of a trifluoromethyl group may also enhance its lipophilicity and metabolic stability, which are advantageous for drug design and development.
Uses
Used in Pharmaceutical Industry:
1H-Pyrazole-4-carboxylic acid, 1-[6-(2-hydroxyphenyl)-2-pyridinyl]-5-(trifluoromethyl)-, ethyl ester is used as a potential pharmaceutical agent for its possible biological activity, which can be harnessed to develop new drugs targeting various diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 1H-Pyrazole-4-carboxylic acid, 1-[6-(2-hydroxyphenyl)-2-pyridinyl]-5-(trifluoromethyl)-, ethyl ester is used as a candidate for the development of new agrochemicals, potentially offering novel modes of action for pest and disease control in agriculture.
Used in Drug Design and Development:
1H-Pyrazole-4-carboxylic acid, 1-[6-(2-hydroxyphenyl)-2-pyridinyl]-5-(trifluoromethyl)-, ethyl ester is utilized in drug design and development processes due to its unique physicochemical properties, such as increased lipophilicity and metabolic stability, which can improve the pharmacokinetics and pharmacodynamics of new drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 1128268-02-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,8,2,6 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1128268-02:
(9*1)+(8*1)+(7*2)+(6*8)+(5*2)+(4*6)+(3*8)+(2*0)+(1*2)=139
139 % 10 = 9
So 1128268-02-9 is a valid CAS Registry Number.
1128268-02-9Relevant articles and documents
SOLUBLE GUANYLATE CYCLASE ACTIVATORS
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, (2013/08/28)
This inventions relates to compounds having the structure Formula I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS
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Page/Page column 76, (2009/07/17)
Disclosed are compounds of formula (I) wherein R1 and R2 are independently selected from hydrogen, halo, CF3, C1-4alkyl and allyl; Y represents (II), (III), (IV) or (V) wherein R3 represents CF3 or C1-4alkyl; and R3a represents CF3 or C1-4alkyl.
