112853-63-1

Basic information

• Product Name: 5-Isoxazolol, 4,5-dihydro-3-(3-nitrophenyl)-
• CAS NO: 112853-63-1
• Molecular Formula: C9H8N2O4
• Molecular Weight: 208.174
• Mol File: 112853-63-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Isoxazolol, 4,5-dihydro-3-(3-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolol, 4,5-dihydro-3-(3-nitrophenyl)-(112853-63-1)
• EPA Substance Registry System: 5-Isoxazolol, 4,5-dihydro-3-(3-nitrophenyl)-(112853-63-1)

Safety Data

• Hazardous Substances Data: 112853-63-1(Hazardous Substances Data)

Upstream product

• 7007-35-4 m-nitrobenzonitrile oxide 
• 75-07-0 acetaldehyde 

Downstream Products

• 4264-04-4 3-(3-nitro-phenyl)-isoxazole 

Relevant articles and documents

SYNTHESIS OF 3-ARYL-4,5-DIHYDRO-5-HYDROXY-1,2-OXAZOLES BY REACTION OF SUBSTITUTED BENZONITRILE OXIDES WITH THE ENOLATE ION OF ACETALDEHYDE.

By reaction of substituted benzonitrile oxides with the enolate ion of acetaldehyde (quantitatively generated by the known cycloreversion of THF in the presence of n-butyllithium) a number of 3-aryl-4,5-dihydro-5-hydroxy-1,2-oxazoles (previously unknown or, in two cases, only synthesized by different procedures) have been isolated in high yields.Treatment of such hydroxy-isoxalines with some common bases allows their conversion in high yields into the corresponding isoxazoles.