113049-47-1

Basic information

• Product Name: Methanesulfonamide, N-[4-[[4-(4-nitro-3-pyridinyl)-1-piperazinyl]acetyl]phenyl]-, N-oxide
• CAS NO: 113049-47-1
• Molecular Formula: C18H21N5O6S
• Molecular Weight: 435.461
• Mol File: 113049-47-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanesulfonamide, N-[4-[[4-(4-nitro-3-pyridinyl)-1-piperazinyl]acetyl]phenyl]-, N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonamide, N-[4-[[4-(4-nitro-3-pyridinyl)-1-piperazinyl]acetyl]phenyl]-, N-oxide(113049-47-1)
• EPA Substance Registry System: Methanesulfonamide, N-[4-[[4-(4-nitro-3-pyridinyl)-1-piperazinyl]acetyl]phenyl]-, N-oxide(113049-47-1)

Safety Data

• Hazardous Substances Data: 113049-47-1(Hazardous Substances Data)

Upstream product

• 5577-42-4 N-[4-(2-bromoacetyl)phenyl]methanesulfonamide 

Relevant articles and documents

Piperazinyl-substituted pyridine and imidazole anti-arrhythmic agents

A series of novel 4-substituted piperazinyl-pyridine and 4-substituted piperazinyl-imidazole compounds have been prepared, including their pharmaceutically acceptable salts, wherein the 4-substituent is a lower phenylalkyl group or a derivative thereof further substituted on the phenyl moiety by a sulphamoyl or sulphonylamino group or by a nitro, amino or acetamido group. These particular compounds are useful in therapy as highly effective anti-arrhythmic agents and therefore, are of value in the treatment of various cardiac arrythmias. The most preferred member compound of the series is N-{4-[1-hydroxy-2-(4-[4-pyridinyl]-1-piperazinyl)ethyl]phenyl} methanesulphonamide. Methods for preparing all these compounds from known starting materials are provided.