1130556-55-6Relevant articles and documents
ACYLGUANIDINES AS TRYPTOPHAN HYDROXYLASE INHIBITORS
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Page/Page column 51, (2015/06/25)
The present invention is directed to acylguanidines which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPHl), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.