1131737-05-7

Basic information

• Product Name: (R)-1-(2,6-dichlorophenyl)ethanaMine hydrochloride
• Synonyms: (1R)-1-(2,6-DICHLOROPHENYL)ETHYLAMINE;(R)-1-(2,6-dichlorophenyl)ethanaMine hydrochloride
• CAS NO: 1131737-05-7
• Molecular Formula: C8H10Cl3N
• Molecular Weight: 226.5307
• Mol File: 1131737-05-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-1-(2,6-dichlorophenyl)ethanaMine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(2,6-dichlorophenyl)ethanaMine hydrochloride(1131737-05-7)
• EPA Substance Registry System: (R)-1-(2,6-dichlorophenyl)ethanaMine hydrochloride(1131737-05-7)

Safety Data

• Hazardous Substances Data: 1131737-05-7(Hazardous Substances Data)

Usage

General Description

(R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride, also known as [R]-(-)-norephedrine hydrochloride, is a chemical compound that belongs to the class of phenethylamines. It is a derivative of amphetamine and is commonly used as a decongestant and appetite suppressant. (R)-1-(2,6-dichlorophenyl)ethanamine hydrochloride acts as a selective alpha-1 adrenergic receptor agonist, which means it can stimulate certain receptors in the sympathetic nervous system to produce vasoconstriction in blood vessels. It is also used in the synthesis of certain pharmaceuticals and research chemicals. However,

Upstream product

• 121443-78-5 (1S)-N-Trimethylsilyl-1-(2-chlorophenyl)ethylamine 
• 39959-67-6 1-(2-Chloro-phenyl)-ethylamine 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 53066-19-6 1-(2',6'-dichlorophenyl)-ethanol 
• 20444-00-2 1,3-dichloro-2-(1-bromoethyl)benzene 
• 121443-77-4 N-<(S)-1-phenylethyl>(trimethylsilyl)amine 
• 68285-26-7 (S)-α-(o-chlorophenyl)ethylamine 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Relevant articles and documents

1-(2,6-Dichlorophenyl)ethylamine: A new and efficient chiral auxiliary for the Staudinger β-lactam synthesis

The diastereoselective synthesis of β-lactams by the Staudinger reaction was examined using chiral imines, derived from substituted 1-phenylethylamines. Among them, 1-(2,6-dichlorophenyl)ethylamine was found to be a new and efficient chiral auxiliary, and the corresponding cis-β-lactams were obtained in good to excellent yields with high diastereoselectivity.

Native Amine-Directed ortho -C-H Halogenation and Acetoxylation /Condensation of Benzylamines

Free or unfunctionalized benzylamines are well known to participate in C-H activation in the presence of palladium salts. Despite the ease with which these complexes can be activated, subsequent functionalization of the dimeric cyclometalates can be chall

Stereoselective Nucleophilic Additions to the Carbon-Nitrogen Double Bond. 2. Chiral Iminium Ions Derived from "Second Generation" Chiral Amines

"Second generation" chiral amines (1S)-(-)-1-(2-chlorophenyl)ethylamine (4) and (1S)-(-)-1-(2,6-dichlorophenyl)ethylamine (5) have been prepared from commercially available (S)-(-)-α-phenethylamine.These chiral reagents have been incorporated into chiral