113214-23-6

Basic information

• Product Name: Thiazole, 2-phenyl-4-(2-thienyl)-
• CAS NO: 113214-23-6
• Molecular Formula: C13H9NS2
• Molecular Weight: 243.353
• Mol File: 113214-23-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Thiazole, 2-phenyl-4-(2-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 2-phenyl-4-(2-thienyl)-(113214-23-6)
• EPA Substance Registry System: Thiazole, 2-phenyl-4-(2-thienyl)-(113214-23-6)

Safety Data

• Hazardous Substances Data: 113214-23-6(Hazardous Substances Data)

Upstream product

• 193978-23-3 2-thiopheneboronic acid pinacol ester 
• 1003-09-4 2-bromothiophene 
• 141305-40-0 4-bromo-2-phenylthiazole 
• 29683-77-0 2-chloro-1-(thiophen-2-yl)ethanone 
• 2227-79-4 benzenecarbothioamide 

Relevant articles and documents

A guideline for the arylation of positions 4 and 5 of thiazole via Pd-catalyzed cross-coupling reactions

The arylation of thiazoles in 4- and 5-position was investigated in detail. Suzuki-Miyaura and Stille cross-coupling reactions were tested using thiazoles either as halide or organometal species. The obtained results were critically compared to develop he

Comparing the reactivity of the 4- and 5-positions of 2-phenylthiazoles in stille cross-coupling reactions

A systematic study of the cross-coupling capability of 4-and 5-substituted 2-phenylthiazoles under Stille conditions is presented. Two cross-coupling options were investigated: 1) combination of thiazolylstannanes with various aryl(hetaryl) halides and, 2) reaction of halothiazoles with PhSn(Bu) 3 as coupling partner. The results obtained from the cross-coupling reactions on the 4- and 5-positions of the thiazole system were compared regarding the influence of the position of the halide (Br, I) and the Bu 3Sn group on both coupling partners. A broad selection of aromatic and heteroaromatic halides was coupled in order to establish a general reactivity platform for this heterocyclic system. Georg Thieme Verlag Stuttgart.