1134197-17-3Relevant articles and documents
The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3- benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists
Johnson, Dale J.,Forbes, Ian T.,Watson, Steve P.,Garzya, Vincenzo,Stevenson, Graeme I.,Walker, Graham R.,Mudhar, Harminder S.,Flynn, Sean T.,Wyman, Paul A.,Smith, Paul W.,Murkitt, Graham S.,Lucas, Adam J.,Mookherjee, Claudette R.,Watson, Jeannette M.,Gartlon, Jane E.,Bradford, Andrea M.,Brown, Fiona
scheme or table, p. 5434 - 5438 (2011/02/21)
A series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles are reported which were found to be potent and selective muscarinic M1 agonists. By control of the physicochemical characteristics of the series, particularly the li
