113479-65-5

Basic information

• Product Name: 7-AMINO-3-CHLOROMETHYL-3-CEPHEM-4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER, HYDROCHLORIDE
• Synonyms: 7-AMINO-3-CHLOROMETHYL-3-CEPHEM-4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER, HYDROCHLORIDE;ACLE HCL;(6R,7R)-7-Amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester Hydrochloride;7-Amino-3-chloromethyl-3-cephem-4-carboxylic acid p-methoxybenzyl ester, hydrochloride ,95%;(6R,7R)-4-Methoxybenzyl 7-aMino-3-(chloroMethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride;7-AMino-3-chloroMethyl-3-cepheM-4-carboxylic acid p-Methoxybenzyl ester, HCl;7-Amino-3-chloromethyl-3-cephem-4-carboxylic acid p-methoxybenzyl est;4-methoxybenzyl (6R,7R)-7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride
• CAS NO: 113479-65-5
• Molecular Formula: C₁₆H₁₇ClN₂O₄S*ClH
• Molecular Weight: 405.3
• Product Categories: Chiral Reagents;Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 113479-65-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 155-157°C
• Boiling Point: 601.1°C at 760 mmHg
• Flash Point: 317.4°C
• Appearance: Pale yellow solid
• Vapor Pressure: 1E-14mmHg at 25°C
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 7-AMINO-3-CHLOROMETHYL-3-CEPHEM-4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER, HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-AMINO-3-CHLOROMETHYL-3-CEPHEM-4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER, HYDROCHLORIDE(113479-65-5)
• EPA Substance Registry System: 7-AMINO-3-CHLOROMETHYL-3-CEPHEM-4-CARBOXYLIC ACID P-METHOXYBENZYL ESTER, HYDROCHLORIDE(113479-65-5)

Safety Data

• Hazardous Substances Data: 113479-65-5(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Solid

Uses

Cefazolin intermediate as antibacterials.

InChI:InChI=1/C16H17ClN2O4S.ClH/c1-22-11-4-2-9(3-5-11)7-23-16(21)13-10(6-17)8-24-15-12(18)14(20)19(13)15;/h2-5,12,15H,6-8,18H2,1H3;1H/t12?,15-;/m0./s1

Upstream product

• 104146-10-3 p-methoxybenzyl 7β-(2-phenylacetamido)-3-chloromethyl-3-cephem-4-carboxylate 
• 104146-10-3 p-methoxybenzyl 7β-phenylacetamido-3-chloromethylcephalosporinate 

Downstream Products

• 110198-97-5 (5S,7S)-7-Amino-3-chloromethyl-7-methoxy-5,8-dioxo-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 110198-97-5 (5S,7R)-7-Amino-3-chloromethyl-7-methoxy-5,8-dioxo-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 110198-96-4 C₁₇H₁₇ClN₂O₅S₂ 

Relevant articles and documents

Novel efficient preparation method of ceftiofur sulfate intermediate

The invention discloses a novel efficient preparation method of ceftiofur sulfate intermediate. Specifically, the invention relates to a novel efficient preparation method of ceftiofur sulfate intermediate, which relates to a ceftiofur sulfate intermediate shown in formula (II) and the preparation method thereof, the preparation method is short in reaction time and high in yield.