1135032-28-8 Usage
Description
1-(3-Phenoxyphenyl)piperidine is a chemical compound with the molecular formula C18H21NO. It is a piperidine derivative featuring a phenoxyphenyl group attached to the piperidine ring. This versatile compound has demonstrated a range of pharmacological activities, such as acting as a serotonin reuptake inhibitor, a potential antipsychotic, and a potential analgesic. It has also been considered for its potential as a novel antidepressant and has shown promise in the treatment of neurological disorders and as a therapeutic target for certain central nervous system disorders.
Uses
Used in Pharmaceutical Industry:
1-(3-Phenoxyphenyl)piperidine is used as a serotonin reuptake inhibitor for its ability to modulate serotonin levels in the brain, which can be beneficial in treating various mood and anxiety disorders.
1-(3-Phenoxyphenyl)piperidine is used as a potential antipsychotic agent for its potential to manage psychotic symptoms, offering a new avenue for the treatment of schizophrenia and other psychotic disorders.
1-(3-Phenoxyphenyl)piperidine is used as a potential analgesic for its capacity to provide pain relief, which could be advantageous in managing chronic and acute pain conditions.
1-(3-Phenoxyphenyl)piperidine is used as a novel antidepressant candidate due to its potential to alleviate symptoms of depression, offering a new approach to treatment.
Used in Neurological Disorder Treatment:
1-(3-Phenoxyphenyl)piperidine is used as a therapeutic target for the treatment of neurological disorders, given its potential to address underlying mechanisms contributing to such conditions.
Used in Central Nervous System Disorder Management:
1-(3-Phenoxyphenyl)piperidine is used as a target for the development of treatments for central nervous system disorders, due to its demonstrated potential in influencing relevant neurological pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 1135032-28-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,5,0,3 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1135032-28:
(9*1)+(8*1)+(7*3)+(6*5)+(5*0)+(4*3)+(3*2)+(2*2)+(1*8)=98
98 % 10 = 8
So 1135032-28-8 is a valid CAS Registry Number.
1135032-28-8Relevant articles and documents
Practical and regioselective amination of arenes using alkyl amines
Ruffoni, Alessandro,Juliá, Fabio,Svejstrup, Thomas D.,McMillan, Alastair J.,Douglas, James J.,Leonori, Daniele
, p. 426 - 433 (2019)
The formation of carbon–nitrogen bonds for the preparation of aromatic amines is among the top five reactions carried out globally for the production of high-value materials, ranging from from bulk chemicals to pharmaceuticals and polymers. As a result of this ubiquity and diversity, methods for their preparation impact the full spectrum of chemical syntheses in academia and industry. In general, these molecules are assembled through the stepwise introduction of a reactivity handle in place of an aromatic C–H bond (that is, a nitro group, halogen or boronic acid) and a subsequent functionalization or cross-coupling. Here we show that aromatic amines can be constructed by direct reaction of arenes and alkyl amines using photocatalysis, without the need for pre-functionalization. The process enables the easy preparation of advanced building blocks, tolerates a broad range of functionalities, and multigram scale can be achieved via a batch-to-flow protocol. The merit of this strategy as a late-stage functionalization platform has been demonstrated by the modification of several drugs, agrochemicals, peptides, chiral catalysts, polymers and organometallic complexes.
