1135150-69-4Relevant articles and documents
Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors
Rheault, Tara R.,Caferro, Thomas R.,Dickerson, Scott H.,Donaldson, Kelly H.,Gaul, Michael D.,Goetz, Aaron S.,Mullin, Robert J.,McDonald, Octerloney B.,Petrov, Kimberly G.,Rusnak, David W.,Shewchuk, Lisa M.,Spehar, Glenn M.,Truesdale, Anne T.,Vanderwall, Dana E.,Wood, Edgar R.,Uehling, David E.
scheme or table, p. 817 - 820 (2009/08/15)
Two new series of potent and selective dual EGFR/ErbB-2 kinase inhibitors derived from novel thienopyrimidine cores have been identified. Isomeric thienopyrimidine cores were evaluated as isosteres for a 4-anilinoquinazoline core and several analogs conta