113712-08-6

Basic information

• Product Name: L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE
• Synonyms: ARGININE-AMC 2 HCL;CATHEPSIN H SUBSTRATE II, FLUOROGENIC;H-ARG-AMC 2 HCL;H-ARG-AMC HCL;L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE;L-Arginine7-amido-4-methylcoumarin2HCl;H-ARG-AMC 2 HCI;H-L-Arg-AMC*2HCl
• CAS NO: 113712-08-6
• Molecular Formula: C16H23Cl2N5O3
• Molecular Weight: 404.29
• Mol File: 113712-08-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Storage Temp.: -15°C
• CAS DataBase Reference: L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE(113712-08-6)
• EPA Substance Registry System: L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE(113712-08-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 113712-08-6(Hazardous Substances Data)

Usage

Description

L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE is a sensitive fluorogenic substrate used for the assay of cathepsin H. It is a white to light brown crystalline powder with unique chemical properties that make it suitable for this specific application.

Uses

Used in Biochemical Research:
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE is used as a sensitive fluorogenic substrate for the assay of cathepsin H, a lysosomal protease enzyme. This application is crucial in biochemical research for studying the activity and function of cathepsin H, which plays a significant role in various biological processes, including protein degradation and immune response regulation.
Used in Pharmaceutical Development:
In the pharmaceutical industry, L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE can be utilized as a tool in drug discovery and development. Its ability to act as a substrate for cathepsin H makes it a valuable compound for identifying and optimizing potential therapeutic agents targeting this enzyme. This can contribute to the advancement of treatments for various diseases and conditions associated with cathepsin H dysregulation.
Used in Diagnostic Applications:
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE can also be employed in diagnostic applications to assess cathepsin H activity levels in biological samples. This can be particularly useful in clinical settings for monitoring disease progression, evaluating treatment efficacy, and predicting patient outcomes in conditions where cathepsin H activity is implicated.
Overall, L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE is a versatile compound with applications in biochemical research, pharmaceutical development, and diagnostic applications, primarily due to its role as a sensitive fluorogenic substrate for the assay of cathepsin H.

InChI:InChI=1/C16H21N5O3/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20)/p+2/t12-/m0/s1